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Aseptic bone necrosis (ABN), also called avascular necrosis or osteonecrosis, is where bone and marrow die in the absence of an infective agent. It can affect any bone, and half of cases show multiple sites of damage, but primarily affects the joints at the shoulder, knee, and hip.

The condition shows necrosis anywhere in the bone. Damage within the length of the bone is usually asymptomatic. Necrosis in the epiphysis or in the bone joints, which extends into adjacent cartilage is more serious. All dead bone cells are, eventually, reabsorbed and replaced. But new bone is soft, may misshape or fracture under pressure producing malformed joint surfaces and hence pain and mobility problems, afflictions such as arthritis. These joints must be treated surgically, by replacement.

It can be caused by a number of conditions that damage bone cells, including fractures, vascular compression, hypertension, vasculitis, thrombosis, the use of corticosteroids, and damage from radiation.

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RT @Dr_Khalifeh: Osteonecrosis of the Jaw Associated With Bisphosphonate Therapy http://ow.ly/Q2k9
aksarkar66 (Ashish Kumar Sarkar) Sun, 03 Jan 2010 18:00:02 -0000
RT @Dr_Khalifeh: Osteonecrosis of the Jaw Associated With Bisphosphonate Therapy http://ow.ly/Q2k9
www.ToothTime.ca Osteonecrosis Jaw: ATM - Fundamentals of Diagnostic http://bit.ly/7cCkbi
Dr_Tania (TANIA KOVALUK) Sat, 02 Jan 2010 17:45:46 -0000
www.ToothTime.ca Osteonecrosis Jaw: ATM - Fundamentals of Diagnostic http://bit.ly/7cCkbi
Hip surgery in sickle cell patients: Sickle cell patients often suffer from avascular necrosis or osteonecrosis.  ... http://bit.ly/7ut8CP
akvenkat (VENKATACHALAM.A.K) Sat, 02 Jan 2010 10:58:16 -0000
Hip surgery in sickle cell patients: Sickle cell patients often suffer from avascular necrosis or osteonecrosis.  ... http://bit.ly/7ut8CP
osteonecrosis of jaw in ppl w/ cancer receiving zoledronic acid 4 bone metastases http://bit.ly/4KLEG7
newtrials_ (New Clinical Trials) Sat, 02 Jan 2010 04:06:22 -0000
osteonecrosis of jaw in ppl w/ cancer receiving zoledronic acid 4 bone metastases http://bit.ly/4KLEG7
osteonecrosis of jaw in ppl w/ cancer receiving zoledronic acid 4 bone metastases http://bit.ly/4KLEG7
_clinical_trial (Clinical Trials) Sat, 02 Jan 2010 03:58:30 -0000
osteonecrosis of jaw in ppl w/ cancer receiving zoledronic acid 4 bone metastases http://bit.ly/4KLEG7
osteonecrosis of jaw in ppl w/ cancer receiving zoledronic acid 4 bone metastases http://bit.ly/4KLEG7
localtrials (US Clinical Trials ) Sat, 02 Jan 2010 03:58:21 -0000
osteonecrosis of jaw in ppl w/ cancer receiving zoledronic acid 4 bone metastases http://bit.ly/4KLEG7

 
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Avascular Necrosis - Offers a personal story since contracting this disease. Including information and a diary.

Dr Yoon's Osteonecrosis Clinic - Describes information about osteonecrosis (avascular necrosis aseptic necrosis AVN ON) of femoral head which is a disabling disease developed in the hip joint.

Kienbock's Disease - Australia - A support and information group in Australia interacting by message or chat room for people with avascular necrosis of the lunate.
Meta Description: [ KienbockDisease_Australia: KienbockDisease Australia Support & Info ]

Legg Perthes Support Group International - Part of the National Osteonecrosis Foundation, offering encouragement, medical information, online discussions and a message board.
Meta Description: [ Legg Perthes Support Group for families dealing with the disease. ]

Osteonecrosis Listserver - Internet forum for osteonecrosis (also called avascular necrosis) offering information and support.
Meta Description: [ osteonecrosis: self-help group list-serv, designed to be an open forum for those having experience with the chronic disorder of osteonecrosis ]

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