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Scleroderma is a rare, chronic disease characterized by excessive deposits of collagen. Progressive systemic scleroderma or systemic sclerosis, the generalised type of the disease, can be fatal. The localised type of the disease tends not to be fatal. The term 'localised, generalised sclerderma' can be used to describe cases where the disease covers a large area of the body - typically more than 40%.

Signs and symptoms


Scleroderma affects the skin, and in more serious cases it can affect the blood vessels and internal organs. The most evident symptom is the hardening of the skin and associated scarring. Typically, the skin appears reddish or scaly in appearance. Blood vessels may also be more visible. Where large areas are affected, fat and muscle wastage will weaken limbs and affect appearance.

The seriousness of the disease varies hugely between cases. The two most important factors to consider are the level of internal involvement (beneath the skin) and the total area covered by the disease. For example, there have been cases where the patient has no more than one or two lesions (affected areas), perhaps covering a few inches. Less serious cases tend not to involve the internal bodily functions.

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Arthritis
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OMG! I Found out over the weekend my cousin is dying from Scleroderma =o( and she has 5 kids =o( she has 6 months or less
JessicaLUVRenee (Jessica Renee) Mon, 14 Dec 2009 16:41:35 -0000
OMG! I Found out over the weekend my cousin is dying from Scleroderma =o( and she has 5 kids =o( she has 6 months or less
What is the cause for the scleroderma? http://bit.ly/6M7TG1
iMedixQnA (iMedix Q&A) Mon, 14 Dec 2009 09:51:16 -0000
What is the cause for the scleroderma? http://bit.ly/6M7TG1
My sis needs something to stop #scleroderma from tearing her up inside. Donate at scleroderma.org in honor of Tracy Hazel. #mycharity
Kinravip (Rob Pivarnik) Mon, 14 Dec 2009 04:30:10 -0000
My sis needs something to stop #scleroderma from tearing her up inside. Donate at scleroderma.org in honor of Tracy Hazel. #mycharity
was sick w/the flu 2 times already. better now. i was diagnosed w/lupus, scleroderma, pah, grandmal seizures and low thyroid. follow me???
DYvette79 (Danielle Nowak) Fri, 11 Dec 2009 17:48:37 -0000
was sick w/the flu 2 times already. better now. i was diagnosed w/lupus, scleroderma, pah, grandmal seizures and low thyroid. follow me???
Antioxidant for Scleroderma: Healthy Recipe for Scleroderma ... http://bit.ly/6otgeO
FoodMedic (Gary Novosel) Fri, 11 Dec 2009 16:37:43 -0000
Antioxidant for Scleroderma: Healthy Recipe for Scleroderma ... http://bit.ly/6otgeO
To learn more about Scleroderma go to http://www.scleroderma.org and follow @scleroderma, become a fan on FB, subscribe on YouTube/elord27.
jrsnyderjr (JR Snyder Jr) Fri, 11 Dec 2009 00:40:43 -0000
To learn more about Scleroderma go to http://www.scleroderma.org and follow @scleroderma, become a fan on FB, subscribe on YouTube/elord27.

 
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About.com: Scleroderma - News, information, and support for patients with scleroderma.
Meta Description: [ Scleroderma cause, diagnosis, symptoms, and treatment. Scleroderma (systemic sclerosis) is both a rheumatic disease and a connective tissue disease. Scleroderma is actually a symptom of a group of diseases complicated by abnormal growth of connective tissue. The two main classes are localized scl... ]

International Scleroderma Network - Resource for medical and support information including symptoms, treatments, clinical trials, and support group listings.

Juvenile Scleroderma Network, Inc. - Organization that is working to provide educational programs about JSD, and to help children and their families to gain a better understanding.

Scleroderma - Information from the Arthritis Foundation.
Meta Description: [ Arthritis Foundation ]

Scleroderma - Information from the Mayo Clinic.
Meta Description: [ Scleroderma — Comprehensive overview covers symptoms and treatment of this disease that involves skin thickening. ]

Scleroderma - Handout from the National Institutes of Health.

404 Scleroderma - Information sheet.
Meta Description: [ Hunter Area Pathology Service, Australia, The Hunter Region's quality pathology provider ]

Scleroderma Clinical Trials Consortium - Information about this international organization which is dedicated to finding a better treatment for this disorder. Includes current studies and a newsletter.
Meta Description: [ An international organization dedicated to finding better treatment for scleroderma. ]

Scleroderma Society - Offers support and information. Includes an introduction, news and a message board.
Meta Description: [ scleroderma society web site ]

Scleroderma Society of Canada - A non-profit society raising awareness of and funding for research and a cure. Good factual information about this disease.

The Scleroderma Foundation - National nonprofit health organization with 14,000 members, dedicated to a three-fold mission of support, education, and research to help fight this challenging autoimmune disease.
Meta Description: [ The Scleroderma Foundation is a national nonprofit health organization dedicated to a three-fold mission of Support, Education, and Research to help fight this challenging autoimmune disease. ]

The Scleroderma Research Foundation - Information about the organization, research, mailing list and resources.

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