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Osteogenesis imperfecta is a group of genetic bone disorders. It is one of the brittle bone diseases. People with OI either have less collagen than normal or the quality is poorer than normal. As collagen is an important protein in bone structure, this impairment causes those with the condition to have weak or fragile bones.*

As a genetic disorder, OI is an autosomal dominant defect. Most people with OI receive it from a parent but it can also be an individual (de novo or "sporadic") mutation.

Types


There are four types of OI, though the symptoms range from person to person. Type I is the most common and mildest form, followed by Type II, Type III and Type IV. Types V and VI have been more recently classified, and they share the same clinical features of IV, but each have unique histologic findings.

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Dwarfism :: Congenital Anomalies
Osteoporosis :: Musculoskeletal Disorders
Rare Disorders :: Conditions and Diseases

 
Osteogenesis_Imperfecta RSS feed directory of related sites

Brittle Bone Society - The UK charity providing support for people with osteogenesis imperfecta.
Meta Description: [ The Brittle Bone Society is a UK charity providing support to people affected by the rare genetic bone condition Osteogenesis Imperfecta. ]

Children's Brittle Bone Foundation Website - US organization. Online grant and fellowship applications with news about recent and upcoming events.

404 Osteogenesis Imperfecta - Fact sheets from the National Institutes of Health.

Osteogenesis Imperfecta - Overview from the University of Maryland.
Meta Description: [ Overview of osteogenesis imperfecta ]

Osteogenesis Imperfecta Federation Europe - Information on Osteogenesis Imperfecta around Europe
Meta Description: [ Information on Osteogenesis Imperfecta ]

Osteogenesis Imperfecta Foundation - Supports and encourages medical research and disseminates information to patients, their families, and medical professionals

Osteogenesis imperfecta hub - Links to overviews, clinical trials, images, research articles and abstracts for osteogenesis imperfecta.
Meta Description: [ ancestor dna paternity home testing free test kit mitral valve ]

Osteogenesis Imperfecta Information - Resources gathered by the mother of a child with the disease. Includes a personal page about her son Jojo, his disease, treatment, and progress.

Osteogenesis Imperfecta: The Links to Nutrition - Reviews the possible role of nutrition in this disorder. Questions whether it is solely a genetic condition.
Meta Description: [ Explores the possible role of diet and nutrition in osteogenesis imperfecta. ]

The Osteogenesis Imperfecta Mailing List - For the discussion of any issues relating to OI. Open to both professionals and families.

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