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Poliomyelitis, often called polio or infantile paralysis, is a viral paralytic disease. The causative agent, a virus called poliovirus (PV), enters the body orally, infecting the intestinal wall. It may proceed to the blood stream and into the central nervous system causing muscle weakness and often paralysis. An ancient disease, it was first recognized as a medical entity by Jakob Heine in 1840. Eradication efforts led by the World Health Organization and The Rotary Foundation of Rotary International have reduced the number of annual diagnosed cases from the hundreds of thousands to around a thousand.

Infection


Polio is a communicable disease which is categorized as a disease of civilization. Polio spreads through human-to-human contact, usually entering the body through the mouth due to fecally contaminated water or food. The poliovirus is a small RNA (ribonucleic acid) virus that has three different strains and is extremely infectious. The virus invades the nervous system, and the onset of paralysis can occur in a matter of hours. While polio can strike a person at any age, over fifty percent of the cases occur in children between the ages of three and five.

The incubation period of polio, from the time of first exposure to first symptoms, ranges from three to thirty five days, thus Polio can spread widely before a polio outbreak is apparent. Most people infected with the poliovirus have no symptoms or outward signs of the illness and are thus never aware they have been infected. After initial infection with poliovirus, virus particles are excreted in the feces for several weeks and are highly transmissible to others in a community. In all forms of polio, the early symptoms of infection are fatigue, fever, vomiting, headache and pain in the neck and extremities. Around 1% of unimmunized people develop paralytic complications, in some cases bulbar paralysis.

The cause of the disease


Initial infection is of cells in the lining of the small intestine. Immunization interrupts the process here. After multiplication there, viraemia occurs, with distribution of virus to other parts of the body. Flu-like symptoms are typical of viraemia from any cause. The virus has an affinity for the cell bodies of motor neurones, which carry commands to the muscles.

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@JamieFisherr poliomyelitis is a virus? Then the antigen will be just a killed polio virus used in vaccine to immu (cont) http://tl.gd/17p1g
liamhassan (Liam Hassan) Fri, 11 Dec 2009 20:58:28 -0000
@JamieFisherr poliomyelitis is a virus? Then the antigen will be just a killed polio virus used in vaccine to immu (cont) http://tl.gd/17p1g
Omg!!! Poliomyelitis is hella sad!!! ))):
Elyzablahhhd (serranoelyza) Wed, 09 Dec 2009 02:54:37 -0000
Omg!!! Poliomyelitis is hella sad!!! ))):
Charcot-Marie Tooth disease.. Poliomyelitis.. Guillain-Barre Syndrome..
cheeeeese31 (cheeeeeesssse) Tue, 08 Dec 2009 11:56:09 -0000
Charcot-Marie Tooth disease.. Poliomyelitis.. Guillain-Barre Syndrome..
Tetanus, Diphtherie, Poliomyelitis, Pertussis: links; H1N1 : rechts -- Wenn schon Scheisse, dann Scheisse mit Schwung...
quatze (Mat) Mon, 07 Dec 2009 15:00:03 -0000
Tetanus, Diphtherie, Poliomyelitis, Pertussis: links; H1N1 : rechts -- Wenn schon Scheisse, dann Scheisse mit Schwung...

 
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A World without Polio - Highlights the efforts for world-wide eradication of polio by UNICEF and its partners.
Meta Description: [ The United Nations Children's Fund - UNICEF - works for children's rights, their survival, development and protection, guided by the Convention on the Rights of the Child. ]

Global Polio Eradication Initiative - WHO official site on the initiative, with background information and data on current progress to completely eradication polio.

MedlinePlus: Polio and Post-Polio Syndrome - Directory of news, articles, and factsheets.
Meta Description: [ Polio and Post-Polio Syndrome ]

National Polio Surveillance Project - Contains polio surveillance data for India updated weekly, with information and documents on the Polio Eradication Programme.

Polio Eradication Project - Information about the drive from International Broadcasting Bureau.

Polio Experience Network - Offers information, inspiration, ideas and resources to help you understand polio and post-polio syndrome, and to confidently manage life with it.
Meta Description: [ Large post-polio resource. Topics ranging from medical and inspirational material to support issues to www resources and more. ]

Polio Facts - Factsheet with caose, symptoms, risk factors, diagnosis, complications, treatment, and prevention.

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