Ehrlichiosis (also known as canine rickettsiosis, canine hemorrhagic fever, canine typhus, tracker dog disease, and tropical canine pancytopenia) is a tick-borne disease of dogs usually caused by the organism Ehrlichia canis, or less commonly Ehrlichia chaffenesis and E. equii. German Shepherd dogs are thought to be particularly affected by the disease, but cats and humans can also be infected. There is also the Human Granulocytic Anaplasmosis which is caused by Anaplasma phagocytophilum (formerly known as Ehrlichia phagocytophilia).
Ehrlichia
Ehrlichia is a
rickettsial bacteria belonging to the family
Ehrlichiaceae. There are several species of
Ehrlichia, but the one that most commonly affects dogs and causes the most severe clinical signs is
Ehrlichia canis. This species infects
monocytes in the peripheral blood. The brown dog tick, or
Rhipicephalus sanguineous, that passes the organism to the dog is prevalent throughout most of the
United States, but most cases tend to occur in the Southwest and Gulf Coast regions where there is a high concentration of the tick.
Ehrlichia is found in many parts of the world and was first recognized in
Algeria in 1935. During the
Vietnam War ehrlichiosis became well known as a dog disease due to the infection and death of many military working dogs.
Disease Overview
Dogs get ehrlichiosis from the brown dog tick, which passes an ehrlichia organism into the bloodstream when it bites. It is also possible for dogs to become infected through a
blood transfusion from an infected dog.
There are three stages of ehrlichiosis, each varying in severity. The acute stage, occurring several weeks after infection and lasting for up to a month, can lead to fever and lowered peripheral blood cell counts due to
bone marrow suppression. The second stage, called the subclinical phase, has no outward signs and can last for the remainder of the dog's life, during which the dog remains infected with the organism. Some dogs are able to successfully eliminate the disease during this time. In some dogs the third and most serious stage of infection, the chronic phase, will commence. Very low blood cell counts (
pancytopenia),
bleeding, bacterial infection, lameness,
neurological and
ophthalmic disorders, and
kidney disease, can result. Chronic ehrlichiosis can be fatal.
More on
[ Ehrlichiosis ]
Vector Borne
Zoonoses
Ticks :: Ticks and Mites
Ehrlichiosis - Short scientific article with bibliography on the disease in humans and animals.
Ehrlichiosis - Description of the disease and diagnostic tests.
Ehrlichiosis Facts - Newly discovered rickettsial diseases transmitted by ticks. Includes symptoms, treatment, and prevention.
Emergence of the Ehrlichioses as Human Health Problems - Scientific and medical article on the disease.
Human Ehrlichioses in the United States - Short article from the Centers for Disease Control and Prevention.
Species Jump: Human Ehrlichiosis- Mutant or Emergence? - Research article on the disease. Includes organism description, similar organisms, symptoms, bibliography, and speculation on the origin of the rickettsia.