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Bartonella is a Gram-negative genus of bacterium, some of which are extra-cellular, opportunisitc human pathogens.

Bartonella Infection Cycle


The currently accepted model explaining the infection cycle is the following: In general case, the transmitting vectors are blood-sucking arthropods and the reservoir hosts are mammals. Immediately after infection, the bacteria colonize a primary niche, the endothelial cells. Every 5 days, a part of the Bartonella in the endothelial cells are released in the blood stream where they infect erythrocytes. The bacteria then invade and replicate within a phagosomal membrane inside the erythrocytes. Inside the erythrocytes, the Bartonella keeps multiplying until a certain density, where the erythrocyte is still "working" properly. At this point, the Bartonella has simply to wait until it is taken with the erythrocytes by a blood-sucking arthropod.

Pathophysiology (Humans)


Humans as reservoir host:

B.bacilliformis

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RT @mercola: RT @rawknrollariane: @mercola Thank you SO much 4 your #Lyme article!! I'm a Chronic Lyme & Bartonella survivor who got it into remission...
iamtheiamthat (Mary Scarborough) Mon, 06 Feb 2012 09:29:12 -0000
RT @mercola: RT @rawknrollariane: @mercola Thank you SO much 4 your #Lyme article!! I'm a Chronic Lyme & Bartonella survivor who got it into remission...
RT @rawknrollariane: @mercola Thank you SO much 4 your #Lyme article!! I'm a Chronic Lyme & Bartonella survivor who got it into remission...
mercola (Dr. Mercola) Mon, 06 Feb 2012 09:25:22 -0000
RT @rawknrollariane: @mercola Thank you SO much 4 your #Lyme article!! I'm a Chronic Lyme & Bartonella survivor who got it into remission...
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