Gourt > Health > Conditions and Diseases > Infectious Diseases > Parasitic > Chagas Disease
Human diseases Chagas' disease (also called American trypanosomiasis) is a human tropical parasitic disease which occurs in the Americas, particularly in South America. Its pathogenic agent is a flagellate protozoan named Trypanosoma cruzi, which is transmitted to humans and other mammals mostly by hematophagous assassin bugs of the subfamily Triatominae (Family Reduviidae). Those insects are known by numerous common names varying by country, including benchuca, vinchuca, kissing bug, chipo and barbeiro. The most common insect species belong to the genera Triatoma, Rhodnius, and Panstrongylus. Other forms of transmission are possible, though, such as ingestion of food contaminated with parasites, blood transfusion and fetal transmission.
Trypanosoma cruzi is a member of the same genus as the infectious agent of African sleeping sickness, but its clinical manifestations, geographical distribution, life cycle and insect vectors are quite different.
History
The disease was named after the Brazilian physician and infectologist Carlos Chagas, who first described it in 1909, but the disease was not seen as a major public health problem in humans until the 1960s. He discovered that the intestines of Triatomidae harbored a flagellate protozoan, a new species of the Trypanosoma genus, and was able to prove experimentally that it could be transmitted to marmoset monkeys which were bitten by the infected bug. More on [ Chagas disease ]
Vector Borne
Zoonoses
Heteroptera :: Hemiptera
Oral Transmission of Chagas Disease http://t.co/nEiklI5D
emiliomonteb (Emilio Monte) Sat, 28 Jan 2012 14:30:16 -0000
Oral Transmission of Chagas Disease http://t.co/nEiklI5D
American Trypanosomiasis: Chagas Disease One Hundred Years of Research (Elsevier Insights): Chagas disease cause... http://t.co/8CJwT4Rw
uralylomy (Porche Edley) Sat, 28 Jan 2012 11:36:52 -0000
American Trypanosomiasis: Chagas Disease One Hundred Years of Research (Elsevier Insights): Chagas disease cause... http://t.co/8CJwT4Rw
Bayer trying to tackle neglected tropical diseases: malaria, sleeping sickness&chagas disease & tuberculosis-often not for profit#Access2Med
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as Disease Research Program - Debasish Chattopadhyay's Structural Biology Laboratory is studying the DHFR and PTR enzymes of Trypanosoma cruzi for structure-based design of specific inhibitors of these enzymes. For this purpose, they have determined the crystal structure of substrate and inhibitor complexes of T. cruzi PTR at high resolution.
Chagas Disease - Information from the World Health Organization.
Chagas Disease Facts - Factsheet with cause, symptoms, risk factors, diagnosis, treatment, and prevention.
Chagas' Disease (American Trypanosomiasis) - Brief information about Chagas' and other diseases caused by parasites of the Trypanosomatidae family (leishmaniasis and African sleeping sickness).
Division of Parasitic Diseases - Chagas Disease - Detailed information from the U.S. Centers for Disease Control.
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MedlinePlus: Chagas Disease - Directory of news, articles, and factsheets.
Meta Description: [ Chagas Disease ]
Mitochondrial DNA Sequence Variation among Triatomine Vectors of Chagas' Disease - Full text article by Daniel E Lyman, Fernando A. Monteiro, Ananias A. Escalante, Celia Cordon-Rosales, Dawn M. Wesson, Jean-Pierre Dujardin, and Charles B. Beard.
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The Kiss of Death: Chagas' Disease in the Americas - A study of the disease by Dr. Joseph Bastien.
Trypanosoma cruzi (Chagas' Disease) - Images of the causative parasite and brief information about the disease.
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