Severe Combined Immunodeficiency, or SCID, is a genetic disorder in which both "arms" (B cells and T cells) of the adaptive immune system are crippled, due to a defect in one of several possible genes. SCID is a severe form of heritable immunodeficiency. It is also known as the "bubble boy" disease because its victims are extremely vulnerable to infectious diseases and must live (if untreated) in a completely sterile environment. The most famous case is the boy David Vetter.
SCID affects about 1 in 100,000 live births. These babies, if untreated, usually die within 1 year due to severe, recurrent infections. Chronic diarrhea, ear infections, recurrent Pneumocystis jiroveci pneumonia, and profuse oral candidiasis commonly occur. Treatment options are much improved since David Vetter, and living in a bubble is no longer necessary.
Rare Disorders :: Conditions and Diseases

Forest's Omenn Syndrome Page - Reference links and other information about the disease, and the story of Forest, a little boy and his battle with the illness.
Hope Through Research - A family's struggle with SCID through three generations. Gives history of the research developments in fighting the disease.
The SCID Homepage - Information about the disease with links to journal articles, latest research developments, and patient support.
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