Sjögren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It is named after Swedish ophthalmologist Henrik Sjögren (1899-1986), who first described it. Sjögren's syndrome is also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases. The hallmark symptoms of the disorder are dry mouth and dry eyes (part of what are known as sicca symptoms). In addition, Sjögren's syndrome may cause skin, nose, and vaginal dryness, and may affect other organs of the body, including the kidneys, blood vessels, lungs, liver, pancreas, and brain. Nine out of ten Sjögren's patients are women and the average age of onset is late 40s, although Sjögren's occurs in all age groups in both women and men. It is estimated to strike as many as 4 million people in the United States alone making it the second most common autoimmune rheumatic disease.
Blood tests can be done to determine if a patient has high levels of antibodies that are indicative of the condition, such as anti-nuclear antibody (ANA) and rheumatoid factor, which are associated with autoimmune diseases. Typical Sjögren syndrome ANA patterns are SSA/Ro and SSB/La, of which SSB/La is far more specific; SSA/Ro is associated with numerous other autoimmune conditions but are often present in Sjögren's (Franceschini & Cavazzana I 2005).
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Almark's Sjögren's Syndrome Site - Information about symptoms and diagnosis from a SJS patient, including a FAQ and articles.
Meta Description: [ Sjogren's Syndrome a free information resource site, provided by almark.net ]
eMedicine Health - Sjögren Syndrome - Consumer health resource center providing information on the causes, symptoms, and treatment.
Meta Description: [ Sjögren syndrome is a disorder of the moisture-producing glands, such as the tear ducts and the salivary glands. These glands become infiltrated with white blood cells (lymphocytes) that are part ... ]
Lynne's Sjogren's Syndrome - Symptoms, tips and stories provided by a fellow sufferer.
Meta Description: [ This home page serves as the primary point of access to Lynnes Sjogrens Syndrome Website. ]
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Sjögren's Syndrome Clinic - Research clinic of the US National Institutes for Health. Background information, current clinical studies and current lab studies.
Meta Description: [ NIDCR DIR: Welcome to the Sjögren’s Syndrome Clinic (Index page of Sjögren’s Syndrome Clinic) ]
Sjogren's Syndrome - Easy to read description of the syndrome and its symptoms.
Meta Description: [ The Department of Orthopaedics is actively involved in quality patient care, teaching, and research concerning bone and joint problems. Special areas of expertise include foot and ankle, hand and microvascular, hip and knee, arthritis, sports medicine. ]
Sjogren's Syndrome - A description of this syndrome and a look at the symptoms, diagnosis, and treatments to help with the symptoms.
Meta Description: [ The Department of Orthopaedics is actively involved in quality patient care, teaching, and research concerning bone and joint problems. Special areas of expertise include foot and ankle, hand and microvascular, hip and knee, arthritis, sports medicine. ]
Sjogren's Syndrome - Information page compiled by NINDS, the National Institute of Neurological Disorders and Stroke.
Meta Description: [ Sjogren's Syndrome information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ]
Sjogren's Syndrome Foundation, Inc - Information about the foundation and its membership as well as explanation of this disease, links and news and events.
Sjogren's Syndrome New Zealand - Details about the group and its workshops as well as the disease.
Sjogren's Syndrome: A Guide for the Patient - From Scripps Clinic and Research Foundation
Sjogren's Syndrome: Medstudents - A review of its definition, epidemiology, diagnosis, prognosis and treatment.
Meta Description: [ Sjögren's Syndrome:A review of its definition, epidemiology, diagnosis,prognosis and treatment ]
Sjogren's World - Support in the form of chat rooms, message boards, articles, and links.
Meta Description: [ Sjogren's Syndrome: Sjogren's Syndrome support through Live Chat, Message Boards Forums, Instant Messaging, E-Pals (internet pen pals), articles and links. Sjogrens is an autoimmune disease with many symptoms including but not limited to, neuropathies, dry eyes, dry mouth (xerostomia) and this si... ]
SJSAngels · Sjogren's Angels - Yahoo group offering support and understanding to others that have been diagnosed or are intersted in this condition.
Meta Description: [ SJSAngels: Sjogren's Angels ]
The Swedish Sjögren's Syndrome Association - Non-profit organisation, founded in 1989, provides patients with practical information. Dual language (Swedish/English)
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