Gourt > Health > Conditions and Diseases > Genitourinary Disorders > Kidney > Hemolytic Uremic Syndrome
In medicine, hemolytic-uremic syndrome (or haemolytic-uraemic syndrome, abbreviated HUS) is a disease characterised by microangiopathic hemolytic anemia, acute renal failure and a low platelet count (thrombocytopenia).
Signs and symptoms
The classic childhood case of HUS occurs after bloody diarrhea caused by H7, a strain of E. coli that expresses verotoxin (also called Shiga toxin). The toxin enters the bloodstream, attaches to renal endothelium and initiates an inflammatory reaction leading to acute renal failure (ARF) and disseminated intravascular coagulation (DIC). The fibrin mesh destroys red blood cells and captures thrombocytes, leading to a decrease of both on full blood count.
HUS occurs after 2-7% of all E. coli O157:H7 infections.
More on [ Hemolytic-uremic syndrome ]
Atypical Hemolytic Uremic Syndrome - Atypical HUS, is a rare disease among children causing kidney failure and high blood pressure. Offering support and information including, treatment, symptoms, case studies and research.
404
Kidney Foundation of Canada - A description of hemolytic uremic syndrome, where the bacteria comes from, who develops it, the symptoms and how to prevent E.coli 0157:H7.
Meta Description: [ The Kidney Foundation of Canada funds research and provides information and support to people living with kidney disease. ]
Methodist Health Care System - Hemolytic uremic syndrome, a description, what causes it, possible progression, treatments and statistics for this disease.
Meta Description: [ Methodist Hospital System ]
WebMD - Information about hemolytic uremic syndrome including a definition, causes, incidence, risk factors, symptoms, signs, tests, treatment, prognosis, possible complications and when to call the doctor.
