Gourt > Health > Conditions and Diseases > Genetic Disorders > Smith Magenis Syndrome
Smith-Magenis Syndrome (SMS) is a developmental disorder that affects many parts of the body. The major features of this condition include mild to moderate mental retardation, distinctive facial features, sleep disturbances, and behavioral problems. Smith-Magenis syndrome affects an estimated 1 in 25,000 individuals and has been reported in more than 100 people worldwide.
Common Symptoms
Most children with Smith-Magenis syndrome have a broad, square-shaped face with deep-set eyes, full cheeks, and a prominent lower jaw. The middle of the face and the bridge of the nose often appear flattened. The mouth tends to turn downward with a full, outward-curving upper lip. These facial differences can be subtle in early childhood, but they typically become coarser and more distinctive in later childhood and adulthood.
Disrupted sleep patterns are characteristic of Smith-Magenis syndrome, typically beginning early in life. Affected people may be very sleepy during the day, but have trouble falling asleep and awaken several times each night, due to an inverted circadian rhythm of melatonin.
More on [ Smith-Magenis syndrome ]
Rare Disorders :: Conditions and Diseases
natural history smith-magenis syndrome http://bit.ly/5C2Emp
localtrials (US Clinical Trials ) Fri, 18 Dec 2009 10:06:42 -0000
natural history smith-magenis syndrome http://bit.ly/5C2Emp
natural history smith-magenis syndrome http://bit.ly/5C2Emp
usclinicaltrial (US Clinical Trials) Fri, 18 Dec 2009 09:46:45 -0000
natural history smith-magenis syndrome http://bit.ly/5C2Emp
natural history smith-magenis syndrome http://bit.ly/5C2Emp
recruitingtrial (Recruiting Trials) Fri, 18 Dec 2009 09:06:45 -0000
natural history smith-magenis syndrome http://bit.ly/5C2Emp
NORD: Smith Magenis Syndrome - Offers the synonyms, a general discussion and further resources.
Meta Description: [ National Organization for Rare Disorders is dedicated to helping people with rare, orphan diseases. Rarediseases.org contains information on the prevention, treatment and cure of rare diseases. ]
PRISMS (Parents and Researchers Interested in Smith-Magenis Syndrome) - Details about the international support group organization and its mission as well as the condition. Includes an introduction, diagnosis, parent's corner, meet other people with SMS and educational considerations.
Meta Description: [ PRISMS (Parents and Researchers Interested in Smith-Magenis Syndrome) is a nonprofit organization dedicated to providing information and support to families and professionals of persons with SMS. ]
The CaF Directory - A definition of Smith-Magenis syndrome, its inheritance pattern, pre-natal diagnosis and a support group in the United Kingdom.
Meta Description: [ Contact a Family is a UK charity for families with disabled children. We offer information on specific conditions and rare disorders. ]
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