Gourt > Health > Conditions and Diseases > Genetic Disorders > Schizencephaly
Schizencephaly is a type of Cephalic disorder. This is a rare developmental disorder characterized by abnormal slits, or clefts, in the cerebral hemispheres. Schizencephaly is a form of porencephaly. Individuals with clefts in both hemispheres, or bilateral clefts, are often developmentally delayed and have delayed speech and language skills and corticospinal dysfunction. Individuals with smaller, unilateral clefts (clefts in one hemisphere) may be weak on one side of the body and may have average or near-average intelligence. Patients with schizencephaly may also have varying degrees of microcephaly, mental retardation, hemiparesis (weakness or paralysis affecting one side of the body), or quadriparesis (weakness or paralysis affecting all four extremities), and may have reduced muscle tone (hypotonia). Most patients have seizures and some may have hydrocephalus.
In schizencephaly, the neurons border the edge of the cleft implying a very early disruption in development. There is now a genetic origin for one type of schizencephaly. Causes of this type may include environmental exposures during pregnancy such as medication taken by the mother, exposure to toxins, or a vascular insult. Often there are associated heterotopias (isolated islands of neurons) which indicate a failure of migration of the neurons to their final position in the brain.
Treatment for individuals with schizencephaly generally consists of physical therapy, treatment for seizures, and, in cases that are complicated by hydrocephalus, a shunt.
More on [ Schizencephaly ]
Brain Diseases
Rare Disorders :: Conditions and Diseases
had dreams involving really long words like corticalization, schizencephaly, & hemimegalencephaly. ugh. more googling todayâafter shopping!
benanderin (benanderin) Sat, 31 Oct 2009 15:05:15 -0000
had dreams involving really long words like corticalization, schizencephaly, & hemimegalencephaly. ugh. more googling today—after shopping!
AZ Fair continued: Porencephaly, Schizencephaly, Dandy-Walker Syndrome, Cerebellar Hypoplasia, Microcephaly, and Megalencephaly.
Jeffinphx (Jeff H*****) Wed, 28 Oct 2009 20:20:53 -0000
AZ Fair continued: Porencephaly, Schizencephaly, Dandy-Walker Syndrome, Cerebellar Hypoplasia, Microcephaly, and Megalencephaly.
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Cleveland Clinic - A description of schizencephaly including treatments and prognosis and further reading.
NINDS: Schizencephaly - Information sheet compiled the National Institute of Neurological Disorders and Stroke.
Meta Description: [ Schizencephaly information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ]
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