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Incontinentia Pigmenti (IP) is a genetic disorder that affects the skin, hair, teeth, and nails. It is also known as Bloch Sulzberger syndrome, Bloch Siemens syndrome, melanoblastosis cutis and naevus pigmentosus systematicus.

The skin lesions evolve through characteristic stages:

  1. blistering (from birth to about four months of age),
  2. a wart-like rash (for several months),
  3. swirling macular hyperpigmentation (from about six months of age into adulthood), followed by
  4. linear hypopigmentation.

Alopecia, hypodontia, abnormal tooth shape, and dystrophic nails are observed. Some patients have retinal vascular abnormalities predisposing to retinal detachment in early childhood. Cognitive delays/mental retardation are occasionally seen.

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Therapeutic use of topical corticosteroids in the vesiculobullous lesions of incontinentia pigmenti. http://kele.es/kWz
Sciencia (Webmaster Sciencia) Tue, 24 Nov 2009 01:00:45 -0000
Therapeutic use of topical corticosteroids in the vesiculobullous lesions of incontinentia pigmenti. http://kele.es/kWz

 
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Incontinentia Pigmenti - Informational sheet compiled by National Institute of Neurological Disorders and Stroke.
Meta Description: [ Incontinentia Pigmenti information sheet compiled by the National Institute of Neurological Disorders and Stroke (NINDS). ]

Incontinentia Pigmenti International Foundation - Details about the organization that is dedicated to research into the causes and treatment of this genetic disease. Includes information about the disease, genetics and genes.

Incontinentia Pigmenti: All About Anna - The authors' daughter was diagnosed with IP 6 weeks after birth. This is her story.

MCW Healthlink: Incontinentia Pigmenti - An article about this rare genetic disorder, its stages and symptoms.
Meta Description: [ Incontinentia pigmenti is a rare, genetic disorder characterized by unusual patterns of discolored skin. ]

National Library of Medicine - Bloch-sulzberger syndrome, the synonyms, a summary and major features.

Readers Digest Health: IP - A general discussion about incontinentia pigmenti, with alternate names and further resources.
Meta Description: [ RD.com offers articles, interactive tools, games, and multimedia features from the editors of Reader's Digest. As the official web site of Reader's Digest, it offers information of enduring value and interest to help improve, inspire, and enrich the lives of its users. ]

Vanderbilt Medical Center - An article about incotinentia pigmenti.

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