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This article covers Dysplasia, a pre-cancerous change in cellular structures. For details on Hip dysplasia, a clinical condition affecting the hip joint (especially in dogs), please see the article on Hip dysplasia. Dysplasia (latin for 'bad form') is an abnormality in the appearance of cells indicative of an early step towards transformation into a neoplasia. It is therefore a pre-neoplastic or pre-cancerous change. This abnormal growth is restricted to the epithelial layer, not invading into the deeper tissue. Though dysplasia may regress spontaneously, persistent lesions must be removed, either with surgery, chemical burning, heat burning, burning with laser, or freezing (cryotherapy).

The best known form of dysplasia is the precursor lesions to cervical cancer, called cervical intraepithelial neoplasia (CIN). This lesion is sometimes caused by an infection with the human papilloma virus (HPV). Dysplasia of the cervix is almost always unsuspected by the woman. It is usually discovered by a screening test, the pap smear. The purpose of this test is to diagnose the disease early, while it is still in the dysplasia phase and easy to cure.

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Rare Disorders :: Conditions and Diseases

 
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National Library of Medicine: CNFS - Offers synonyms of craniofrontonasal syndrome, a summary and a list of features.

NORD: Craniofrontonasal Dysplasia - Offers a general discussion and resources.
Meta Description: [ National Organization for Rare Disorders is dedicated to helping people with rare, orphan diseases. Rarediseases.org contains information on the prevention, treatment and cure of rare diseases. ]

OMIM: National Center for Biotechnology Information - A clinical synopsis of Craniofrontonasal Dysplasia.

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