Gourt > Health > Conditions and Diseases > Endocrine Disorders > Adrenal > Pheochromocytoma
A pheochromocytoma (also phaeochromocytoma, English spelling) is a tumor of the medulla of the adrenal glands originating in the chromaffin cells, which secretes excessive amounts of catecholamines, usually epinephrine and norepinephrine. Extra-adrenal paragangliomas (often described as extra-adrenal pheochromocytomas) are closely related, though less common, tumors that originate in the ganglia of the sympathetic nervous system and are named based upon the primary anatomical site of origin.
Inheritance
Up to 25% of pheochromocytomas may be familial. Mutations of the genes VHL, RET, NF1, SDHB and SDHD are all known to cause familial pheochromocytoma/extra-adrenal paraganglioma.
Features
The signs and symptoms of a pheochromocytoma are those of sympathetic nervous system hyperactivity:
- elevated heart rate
- elevated blood pressure. A clue to the presence of phaechromocytoma is the postural fall of systolic blood pressure greater than 10 mmHg on making the patient stand.
- palpitations
- anxiety often resembling that of a panic attack
- diaphoresis
- headaches
stdy evaluating ultratrace iobnguane i 131in ppl w/ malig pheochromocytoma/paraganglioma http://bit.ly/5jTZCb
localtrials (US Clinical Trials ) Sun, 06 Dec 2009 08:46:58 -0000
stdy evaluating ultratrace iobnguane i 131in ppl w/ malig pheochromocytoma/paraganglioma http://bit.ly/5jTZCb
stdy evaluating ultratrace iobnguane i 131in ppl w/ malig pheochromocytoma/paraganglioma http://bit.ly/5jTZCb
usclinicaltrial (US Clinical Trials) Sun, 06 Dec 2009 08:39:02 -0000
stdy evaluating ultratrace iobnguane i 131in ppl w/ malig pheochromocytoma/paraganglioma http://bit.ly/5jTZCb
stdy evaluating ultratrace iobnguane i 131in ppl w/ malig pheochromocytoma/paraganglioma http://bit.ly/5jTZCb
recruitingtrial (Recruiting Trials) Sun, 06 Dec 2009 07:03:01 -0000
stdy evaluating ultratrace iobnguane i 131in ppl w/ malig pheochromocytoma/paraganglioma http://bit.ly/5jTZCb
content validation of quality of life & symptom questionnaires 4 pheochromocytoma & paraganglioma http://bit.ly/7GmmOz
localtrials (US Clinical Trials ) Sat, 05 Dec 2009 19:19:04 -0000
content validation of quality of life & symptom questionnaires 4 pheochromocytoma & paraganglioma http://bit.ly/7GmmOz
content validation of quality of life & symptom questionnaires 4 pheochromocytoma & paraganglioma http://bit.ly/7GmmOz
usclinicaltrial (US Clinical Trials) Sat, 05 Dec 2009 19:11:03 -0000
content validation of quality of life & symptom questionnaires 4 pheochromocytoma & paraganglioma http://bit.ly/7GmmOz
content validation of quality of life & symptom questionnaires 4 pheochromocytoma & paraganglioma http://bit.ly/7GmmOz
recruitingtrial (Recruiting Trials) Sat, 05 Dec 2009 17:33:02 -0000
content validation of quality of life & symptom questionnaires 4 pheochromocytoma & paraganglioma http://bit.ly/7GmmOz
Diagnosis of Pheochromocytoma - Background information, diagrams, and links provided by research scientist, Dr. Graeme Eisenhofer.
Family Practice Notebook: Pheochromocytoma - Comprehensive database of pheochromocytoma. Aimed at primary care providers.
Meta Description: [ Endocrinology: Adrenal Disease: Insufficiency CAH ]
NCI: Malignant Pheochromocytoma - Contains the causes, genetics, treatment, clinical trials, and statistics. From National Cancer Institute.
Meta Description: [ Information about pheochromocytoma treatment, clinical trials, and other topics from the National Cancer Institute. ]
New Technique: Laparoscopic Surgery for Pheochromocytoma - Discussion of different surgical methods for removing this tumor.
Pheochromocytoma - Provides illustrations, symptoms, treatment, prognosis, and complications. From MedlinePlus.
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Pheochromocytoma Group Support Site - Contains an index of links and member sites.
Pheochromocytoma Info - Personal page maintained by a woman with this disorder. Contains a list of experts, testing, treating, and support groups.
Pheochromocytoma Organization - Contains FAQ's, support boards, medical articles, and events.
Meta Description: [ Pheochromocytoma Group Support Organization ]
Pheochromocytoma Organization - Provides group support, information, latest research news, calendar of events, and resources.
Meta Description: [ Pheochromocytoma Group Support Organization ]
Pheochromocytoma Support Board - Features an online help group that is maintained by people diagnosed with pheo.
Meta Description: [ Support board for those with Pheochromocytoma and related adrenal tumors, including Multiple Endocrine Neoplasia, MEN, VHL ]
Pheochromocytoma Website - One man's personal experience with experimental I-131 MIBG treatment for metastatic pheo.
Meta Description: [ A Story of Metastatic Pheochromocytoma
A Personal Testimony of I-131 MIBG Treatment
The Journey to Bio-Chemical Remission ]
Pheochromocytoma: A tumor of the central adrenal - Explains symptoms, diagnosis, tests, and surgical treatment for this condition. By EndocrineWeb.
Meta Description: [ Web's most complete pheo site. Pictures and x-rays help explain this adrenal tumor. Symptoms, diagnosis, and treatment options including laparoscopic surgery. Written by experts for patients, now with a listing of physicians throughout the US. ]
Pheochromocytoma: Special Considerations in Children - Describes the epidemiologic differences between its behavior in the pediatric and adult populations. Aimed at physicians. From Urologic Clinics of North America.
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