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Prevalence of hepatitis B and C and risk factors for nonvaccination in inflammatory bowel disease patients in Northeast France
Mon, 02 Nov 2009 02:15:00 -0800
Data regarding the prevalence of hepatitis C (HCV) and hepatitis B (HBV) in inflammatory bowel disease (IBD) patients are conflicting.In all, 315 IBD (252 Crohn's disease [CD] and 63 ulcerative colitis [UC]) patients were consecutively recruited between June 2005 and May 2009.The median age was 33 years (interquartile range [IQR]: 24-43) and median disease duration was 5 years (IQR: 2-11). Present and/or past HBV and HCV infection was found in 2.86% of 315 patients (CD: HBsAg 0.79%, anti-HBc 2.78%, anti-HCV 0.79%; UC: HBsAg 1.59%, anti-HBc 1.59%, anti-HCV 1.59%). Effective vaccination (anti-HBs without anti-HBc) was present in 48.9% of 315 patients. In multivariate analysis, age at diagnosis over 31 years (odds ratio [OR] 0.29; 95% confidence interval [CI] 0.15-0.58; P = 0.005), disease duration over 7 years (OR 0.43; 95% CI 0.23-0.83; P = 0.005), age at inclusion over 33 years (OR 0.44; 95% CI 0.20-0.94; P = 0.005), and CD (OR 0.29; 95% CI 0.15-0.58; P = 0.005) were associated with the lack of effective vaccination. Two HBsAg-positive patients, including 1 under curative nucleoside/nucleotide analog treatment, had received 6 and 7 infliximab infusions, and 1 HCV RNA-positive subject had been receiving corticosteroid and azathioprine therapies for 12 and 33 months, respectively. No viral reactivation occurred in these patients.The prevalence of HBV and HCV infection in French IBD patients is similar to that of the general population. While the ECCO recommends an effective HBV vaccination in IBD, half of the patients were not vaccinated. The nonvaccination risk factors identified in our study may allow targeted vaccination coverage. (Inflamm Bowel Dis 2009;)
Hepatitis C: Thyroid dysfunction in patients with hepatitis C on IFN-α therapy
IFN-α therapy for hepatitis C is associated with a high prevalence of thyroid dysfunction, which is often irreversible. Two studies have recently investigated the role of HCV, PEG-IFN-α and ribavirin in the development of autoimmune thyroid disorders in patients with hepatitis C on antiviral treatment.
Hepatitis: New hope for difficult cases of autoimmune hepatitis
Autoimmune hepatitis is an inflammatory liver disease of unknown etiology that predominantly affects females, and requires immunosuppressive treatment. A new study investigates the role of mycophenolate mofetil as a rescue treatment for children with the disease.

 

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B - Candidates, doses, and schedules for vaccinations.
Meta Description: [ Lists candidates for vaccinations and provides doses and schedules ]

Acute Viral Hepatitis - Medical information about causes, symptoms, diagnosis, complications, treatment, and prevention of suddenly-occuring inflammation of the liver.

Alcoholic Hepatitis - Discusses the symptoms, treatment, and complications of this liver disease caused by alcohol poisoning.

American Liver Foundation: Getting Hip to Hep - Article explaining how each type is transmitted, risk factors, symptoms, testing, and prevention.

Autoimmune Hepatitis - Discusses liver function, causes of this condition, how it is diagnosed, who is likely to develop it, and treatment to curb the autoimmune response.
Meta Description: [ Jackson Gastroenterology's Web Site includes office information and paient education material on digestive and liver disorders, and nutrition. Endoscopic procedures that help in diagnosis and treatment are also described. ]

Autoimmune Hepatitis - Provides information on the triggers, symptoms, diagnosis, treatment, and complications.
Meta Description: [ Provides information on the triggers, symptoms, diagnosis, treatment, and complications of autoimmune hepatitis. Includes a list of additional resources ]

Chronic Hepatitis - Textbook section provides causes, symptoms, diagnosis and treatment of liver inflammation lasting more than six months.

GayHealth: Hepatitis Resource Center - Information about safe sexual practices, immunization against types A and B, and a risk quiz.
Meta Description: [ GayHealth.com the first worldwide source of health and wellness information for the lesbian, gay, transgender, and bisexual communities founded and operated by lesbian and gay medical professionals. ]

Hepatitis - Learn about symptoms, transmission, prevention, and treatment options for hepatitis A-E and toxic hepatitis. Includes a comparison chart and quiz. [Message board requires free registration.]
Meta Description: [ Learn about the five basic types of hepatitis, ways to avoid contracting hepatitis and treatment options. ]

Hepatitis A-Z - Daniel Dimitriou's site providing extensive information about this disease, including support for spouses of sufferers.

Hepatitis Activist - Help fight liver disease by e-mailing Congress with an automated congressional E-mailer (ACE) system. Also join a list to be kept up to date with liver disease.
Meta Description: [ Hepatitis, Hepatitis C, Hepatitis B, Cirrhosis, and Liver Disease Information Including Hepatitis C and Other Liver Disease Links and Resources., Hepatitis, Hepatitis C, Hepatitis B, Cirrhosis, and Liver Disease Information Including Hepatitis C and Other Liver Disease Links and Resources. ]

Hepatitis Central - Current information on this disease as well as liver disease, cirrhosis, rebetron and interferon. For the medical professional and patient. Online support groups and patient referred physicians.
Meta Description: [ Hepatitis C:All the information you need about Living With Hepatitis C, including the the latest news about infection, transmission, symptoms, treatment breakthroughs and medical progress. ]

Hepatitis Doctor - Discusses hepatitis B and C, interferon treatments, HCV in veterans and prisoners, and effectiveness of maintenance dosage in non-responsive patients.

Hepatitis Magazine Online - Online version for Hepatitis B and C sufferers. Read sample articles, news briefs and personal stories. Subscription links.

404 Hepatitis Magazine: Open Wide - Explains how hepatitis can affect dental health, potential issues, and talking to the dentist about the disease and medications.

Hepatitis Resource Center - Includes chat, information and articles, newsgroups and message boards, books, related web sites, and medical directories on this disease.
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HepQuest - Hepatitis related information for patients and medical professionals.
Meta Description: [ HepQuest is the top source for Hepatitis C on the Web featuring the latest hepatitis information and news for medical professionals and patients. ]

LGBT Health Channel - Contains information and statistics about viral hepatitis.
Meta Description: [ Viral hepatitis is an inflammatory disorder of the liver caused by a virus that can be transmitted through unsafe sex, through feces or bodily fluid, through contaminated food and water, from undercooked shellfish, by using contaminated intravenous drug needles, and through birth. Symptoms inclu... ]

Liver Study Unit, University of Chicago - Provides information about hepatitis for patients, medical students, and physicians.
Meta Description: [ This site describes the services offered at the Liver Study Unit at the University of Chicago Hospitals. ]

MedlinePlus: Hepatitis - Directory of news, articles, and factsheets.
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Viral Hepatitis - Brief description of hepatitis A-E, includes links to detailed information.

Viral Hepatitis: A Through E and Beyond - Explains general symptoms, as well as risk factors, disease spread, prevention, and treatment for each type of virus.
Meta Description: [ Provides information on the symptoms, modes of transmission, at-risk populations, prevention, and treatment for hepatitis A through E. Includes a list of additional resources ]