Introduction

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A synovial sarcoma is one of the rarer types of soft-tissue sarcomas. It is usually found in either the legs or the arms. It usually starts near a major joint in the limb, but, more rarely, it can occur in the neck or torso. It affects more older adolescents and young adults than other age groups, and slightly more women than men.

Causes

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Over 99% of synovial sarcoma cases contain the SYT-SSX fusion gene, the result of a translocation event between chromosomes 18 and X. The diagnosis of synovial sarcoma is usually confirmed by the presence of this genetic trait in a biopsy sample. While the SYT-SSX fusion protein is believed to be the cause of synovial sarcoma, it has not been proven to be tumorigenic in human cell lines.

Symptoms

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Since this is a relatively rare type of cancer, large studies haven't been conducted, but, from the number of cases reported, there is usually a swelling around the affected area, and often there is pain or discomfort (however, some patients can have no pain or discomfort at all). The diagnosis of a synovial sarcoma is by biopsy.

More on [ Synovial sarcoma ]

Synovial Sarcoma - Twitter Search

How often does synovial sarcoma occur? http://t.co/VDmpHRT8
wisteme (D.L.Z.) Sat, 04 Feb 2012 01:41:21 -0000
How often does synovial sarcoma occur? http://t.co/VDmpHRT8
RT @bensfriends: We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
jccolyer (John JC Colyer) Fri, 03 Feb 2012 15:48:36 -0000
RT @bensfriends: We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
bensfriends (Ben's Friends) Fri, 03 Feb 2012 15:46:26 -0000
We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
RT @bensfriends: We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
jccolyer (John JC Colyer) Thu, 02 Feb 2012 20:47:17 -0000
RT @bensfriends: We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
bensfriends (Ben's Friends) Thu, 02 Feb 2012 20:43:45 -0000
We are synovial sarcoma survivors, here for your support. @bensfriends http://t.co/kM4nq814 #bensfriends #payitforward #raredisease
Checking out Nikolas Ritschel's Profile on Synovial Sarcoma - Online Support Group: http://t.co/PUEhPYVH
cookEmonster14 (John Cook) Thu, 02 Feb 2012 07:17:40 -0000
Checking out Nikolas Ritschel's Profile on Synovial Sarcoma - Online Support Group: http://t.co/PUEhPYVH

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