Gourt > Health > Conditions and Diseases > Cancer > Musculoskeletal > Malignant Fibrous Histiocytoma
Malignant fibrous histiocytoma (MFH) is a type of cancer that is the most common soft tissue sarcome of late adult life, most commonly occuring between age 50-70. In rare cases MFH does occur in children, but it is usually in a less aggressive form. It occurs more often in caucasians than those of african or asian descent. Its male:female predominance is 2:1.
MFH occurs most commonly in the extremities and retroperitoneum, but has been reported in many other sites (lung, head/neck, etc.). Development of metastasis depends on the tumor's subtype. Metastasis occurs most frequenly in the lung (90%), bone (8%) and liver (1%). In the extremities, it presents as a painless enlarging soft tissue mass. It can develop anywhere in the soft tissue, but also occurs at sites of previous radiation treatment, shrapnel implantation or next to prostheses. It can be detected by magnetic resonance imaging (MRI), but a biopsy is required for definative diagnosis.
Treatment consists of surgical removal (the extent of which ranges from tumor excision to limb amputation depending on the tumor) and in some cases chemotherapy. Prognosis depends on the primary tumor size and grade (aggressiveness). 5-year survival ranges from 35-60%.
More on [ Malignant fibrous histiocytoma ]
Open clinical trials for Malignant Fibrous Histiocytoma (MFH) patients (sarcoma) - http://bit.ly/2VMmZF
Bruce_S (Bruce Shriver) Mon, 02 Nov 2009 18:24:10 -0000
Open clinical trials for Malignant Fibrous Histiocytoma (MFH) patients (sarcoma) - http://bit.ly/2VMmZF
RT @MaverickNY: Wrtng on pleomorphic undifferentiated sarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, leiomyosarcoma. Head spins
medxcentral (medXcentral (Jim)) Wed, 28 Oct 2009 20:35:13 -0000
RT @MaverickNY: Wrtng on pleomorphic undifferentiated sarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, leiomyosarcoma. Head spins
Writing a report on pleomorphic undifferentiated sarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, leiomyosarcoma... my head spins
MaverickNY (Sally Church) Wed, 28 Oct 2009 20:33:06 -0000
Writing a report on pleomorphic undifferentiated sarcoma, malignant fibrous histiocytoma, rhabdomyosarcoma, leiomyosarcoma... my head spins
eMedicine: Malignant Fibrous Histiocytoma - Article by Doris Yip, MD provides information about soft tissue sarcoma, Malignant Fibrous Histiocytoma, including diagnosis, imaging, intervention, and pictures.
Meta Description: [ Malignant Fibrous Histiocytoma, Soft Tissue - Malignant fibrous histiocytoma (MFH), described by O'Brien and Stout in 1964, is the most common soft tissue sarcoma of late adult ... ]
The Doctors Doctor: Malignant Fibrous Histiocytoma - Brief description of disease, outline includes prognosis, associations, pathogens, and types.
