Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the metaphyseal region of tubular long bones. 50% of cases occur around the knee. It is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone.

CancerBACUP: Osteosarcoma - A childhood cancer that starts in the bone. Provides description of disease, causes, diagnosis, staging, grade, treatment, side effects, and references.
Meta Description: [ Information about osterosarcoma in children describing what it is, symptoms, diagnosis and treatment ]
Childhood Cancer: Osteosarcoma - Information for parents about the most common type of bone cancer. Includes risks, symtoms, diagnosis, various treatments, prognosis, and side effects.
Meta Description: [ Osteosarcoma is the most common type of bone cancer. Boys are more likely to have osteosarcoma than girls, and most cases of osteosarcoma involve the knee. ]
eMedicine: Osteosarcoma - Article by Charles T Mehlman focuses on high-grade intramedullary osteosarcoma, the most common type of bone cancer. Includes introduction, lab studies, histologic findings, treatment, and pictures.
Meta Description: [ Osteosarcoma - This article focuses on high-grade intramedullary osteosarcoma (also referred to as simply osteosarcoma), including its classic osteoblastic form and its fibroblastic and chondroblastic forms. Osteosarcoma is the most common malignant bone tumor (Vander Griend, 1996). It is thought... ]
NCI: Osteosarcoma/Bone Fibrous Histiocytoma - Patient and health professionalal information summaries about the treatment of osteosarcoma/malignant fibrous histiocytoma of bone. Includes description, treatment options, and references.
Meta Description: [ Expert-reviewed information summary about the treatment of osteosarcoma/malignant fibrous histiocytoma of bone. ]
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