Gourt > Health > Conditions and Diseases > Cancer > Musculoskeletal > Bone > Ewing's Sarcoma (2)
Ewing's sarcoma is the common name for primitive neuroectodermal tumor. It is a rare disease in which cancer cells are found in the bone or in soft tissue. The most common areas in which it occurs are the pelvis, the femur, the humerus, and the ribs. James Ewing (1866-1943) first described the tumor, establishing that the disease was separate from lymphoma and other types of cancer known at that time. Ewing's sarcoma occurs most frequently in male teenagers, such as Brandon Russell. Ewing's sarcoma is the result of a translocation between chromosomes 11 and 22, which fuses the EWS gene of chromosome 22 to the FLI1 gene of chromosome 11.
Clinical Findings
Ewing's sarcoma is more common in males and usually presents in childhood or early adulthood, with a peak between 10 and 20 years of age. It can occur anywhere in the body, but most commonly in the pelvis and proximal long tubular bones. The diaphysis of the femur are the most common sites, followed by the tibia and the humerus. Thirty percent are overtly metastatic at presentation.The most common clinical findings are pain and swelling.
More on [ Ewing's sarcoma ]
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Adult Ewings Sarcoma - Information includes definition, risks, detection, treatment, and links.
CancerBACUP: Ewing's Sarcoma - Description of childhood disease, causes, diagnosis, grading, treatment plans, clinical trials, and resources available.
Meta Description: [ Information about Ewing's sarcoma in children describing what it is, symptoms, diagnosis and treatment ]
eMedicine: Ewing Sarcoma and Primitive Neuroectodermal Tumors - Article by Jeffrey A Toretsky, MD about this family of tumors.
Meta Description: [ James Ewing first described Ewing sarcoma in 1921, after observing radiosensitivity in a subgroup of bone tumors. In the ]
eMedicine: Ewing Sarcoma by Ludwig G Strauss, MD - Article about the highly malignant primary bone tumor, first described by James Ewing in 1921. Includes information about frequency, diagnosis, treatment, and disease images.
Meta Description: [ Ewing Sarcoma - Ewing sarcoma, a highly malignant primary bone tumor, was first described by James Ewing in 1921. The tumor is derived from red bone marrow. Most frequently, it is observed in children and adolescents aged 4-15 years and rarely develops in adults older than 30 years. Ewing sarcoma... ]
Ewings Sarcoma Photo Gallery - Rotating photo gallery of patients, E-Sarcoma List, links, and news article.
Shelly Glaspell Ewings Sarcoma Fund - Provides support and advocates for families and patients with Ewings.
Meta Description: [ Ewings Sarcoma Cancer Fund ]
The Adam Dealey Foundation for Ewings Sarcoma - UK charity with aim of increasing awareness of bone cancers that afflict children and young adults.
Meta Description: [ Adam Dealey Foundation for Ewing Sarcoma, is dedicated to funding the Research into Ewing Sarcoma and other Childhood Cancers. ]
The Brian Morden Foundation - Non-profit dedicated to funding research to cure Ewing's sarcoma. Located in Altoona, Pennsylvania.
The Marc Roberts Cancer Fund - Offers information and financial support to those with adult Ewing's Sarcoma.
Meta Description: [ The Marc Roberts Cancer Fund provides financial support and information to Ewing's Sarcoma patients and their caregivers. ]
