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Waldenström macroglobulinemia (WM) is cancer involving a subtype of white blood cells called lymphocytes. It is a type of lymphoplasmacytic lymphoma (LPL), and shares clinical characteristics with nonaggressive non-Hodgkin lymphoma (Cheson, 2006).

It is named after the Swedish physician Jan G. Waldenström (1906-1996), who identified the condition.

History and classification


WM was first described by Jan G. Waldenström (1906-1996) in 1944 in two patients with bleeding from the nose and mouth, anemia, decreased levels of fibrinogen in the blood (hypofibrinogenemia), swollen lymph nodes (lymphadenopathy), increased numbers of lymphocytes in the bone marrow (lymphocytosis), and hyperviscosity of the blood due to increased levels of a class of heavy proteins called macroglobulins (Waldenstrom, 1944).

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collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
newtrials_ (New Clinical Trials) Sat, 02 Jan 2010 10:30:24 -0000
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
localtrials (US Clinical Trials ) Sat, 02 Jan 2010 10:26:25 -0000
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
ustrials (US Trials) Sat, 02 Jan 2010 10:26:23 -0000
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
paidtrials (US Clinical Trials) Sat, 02 Jan 2010 10:22:22 -0000
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
recruitingtrial (Recruiting Trials) Sat, 02 Jan 2010 10:22:19 -0000
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m
goclinicaltrial (Clinical Trials) Sat, 02 Jan 2010 10:18:28 -0000
collecting & storing blood & bone marrow samples from ppl w/ myeloma, waldenstrom's macroglobulinemia, amyloidosis, or http://bit.ly/7bq29m

 
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Dana-Farber Cancer Institute: The Waldenstrom's Macroglobulinemia Program - Cancer resource in Boston, Massachusetts includes information on basic science, research studies, clinical trials, news and events.
Meta Description: [ The Waldenstrom’s Macroglobulinemia program at the Dana-Farber Cancer Institute, a Harvard Medical School affiliate, has spearheaded national and international efforts to bring basic and clinical studies to WM (recently defined as IgM secreting lymphoplasmacytic lymphoma). Our site provides infor... ]

General Practice Notebook: Waldenstrom's macroglobulinemia - Clinically-oriented information outlines clinical features, laboratory results, diagnosis and general treatment matters.

International Waldenstrom's Macroglobulinemia Foundation - Provides information about disease, diagnosis, publications, resources, research, and services.

Questions and Answers on Waldenström’s Macroglobulinemia - National Cancer Institute released bulletin with questions and answers regarding various aspects of disease. Provides information about disease, treatment, and novel drugs.
Meta Description: [ A fact sheet about Waldenström’s macroglobulinemia - a rare, chronic cancer that affects plasma cells and is classified as a low-grade, or indolent, type of lymphoma. National Cancer Institute Fact Sheet 6.4 ]

Research Fund for Waldenstrom's - Non-profit organization located in New York and aimed at promoting research to find a cure. Provides information on resources, published studies and events.
Meta Description: [ Research Fund for Waldenstrom's (RFW) is a volunteer organization whose exclusive purpose is finding a cure for Waldenstrom's Macroglobulinemia (WM) ]

Waldenstrom's Macroglobulinemia Guide - American Cancer Society provides detailed online guide on the disease, including such information as risk factors, causes, prevention, detection, and treatment.

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