Gourt > Health > Conditions and Diseases > Cancer > Gynecologic > Endometrial
The endometrium is the inner membrane in the uterus of mammals, which is developed in preparation for the implantation of a fertilized egg upon its arrival into the uterus. It grows to be rich in glands and blood vessels, which are eventually to be connected to by the pregnancy, forming the placenta through which the embryo, as it becomes a fetus and eventually gestates fully, receives oxygen and is nourished.
The endometrial lining undergoes cyclic regeneration. Most mammals are subject to an estrous cycle, while humans and the great apes display the menstrual cycle. In either situation the endometrium proliferates initially under the influence of estrogen. Once ovulation occurs, in addition to estrogen the ovary will also start to produce progesterone and thereby change the proliferative pattern of the endometrium to a secretory lining. In time the secretory lining provides a hospitable environment to one or more fertilized eggs. If no fertilized egg is detected, the progesterone level drops and the endometrial lining is either reabsorbed (estrous cycle) or shed (menstrual cycle). In the latter, the process of shedding involves the breaking down of the lining, tearing small connective blood vessels, and the loss of the tissue and blood which had constituted it through the vagina, over a series of days. This may be accompanied by some uterine contractions to help expel the menstrual endometrium. In case of implantation, however, the endometrial lining does not get absorbed or shed, but remains as decidua, provides support and protection for the gestation, and becomes part of the placenta.
If there is inadequate stimulation of the lining due to lack of hormones, the endometrium remains thin and inactive. In humans this will result in amenorrhea. The lining after the menopause is often described to be atrophic. In contrast, endometrium that is chronically exposed to estrogens, but not to progesterone, may become hyperplastic.
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About.com: Uterine and Endometrial Cancer - Information about causes, symptoms, diagnosis and treatment.
Meta Description: [ Facts about the causes, symptoms, diagnosis, treatment, and prevention of uterine cancer. Find out if you are at risk of developing uterine or endometrial cancer. ]
BooBoo's Site - One woman's story of endometrial cancer and how it came to be diagnosed.
Meta Description: [ Cancer awareness ]
Cancer Treatment Centers of America: Uterus - Provides information on symptoms, risk factors, diagnosis and treatment. Contact details given.
Meta Description: [ Cancer hospitals for patients who believe in standard, biomedical cancer treatments coupled with alternative cancer therapy. Please explore the CTCA website further to learn about CTCA's uterine cancer treatment options. ]
CancerLinks: Endometrial - Extensive links related to the condition.
Meta Description: [ A New and Novel web site model organizing web pages using Library of Congress Classification. Each page is listed showing author, title, subject and when updated. Our information is credible and current. ]
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Imperial Cancer Research Fund UK - Offers news and information about the risks, detection and treatment of endometrial cancer.
Meta Description: [ Find out all about what cancer is, how it makes people ill, the types of research that Cancer Research UK funds, information summaries for the most commonly diagnosed cancers and a historical perspective on research and treatment. ]
OncologyChannel: Endometrial Cancer - Resources and information on this condition including diagnosis and treatment matters.
Meta Description: [ Uterine cancer is the most common gynecologic cancer (i.e., cancer that originates in female reproductive system). It develops in the body of the uterus, or womb, which is a hollow organ located in the lower abdomen. Endometrial cancer, which originates in the inner lining of the uterus, accounts... ]
Womb - UK site provides information on uterine cancers and includes links, charities, academic organizations and medical institutions.
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