Gourt > Health > Conditions and Diseases > Cancer > Brain and CNS > Medulloblastoma (2)
Medulloblastoma is the most common primary brain tumour in children, with a bimodal incidence at the ages of 4-8 years, then in the early 20s and accounts for ~20% of childhood brain tumors. Males out of female 3:2 or 3:1 in many cases. It is a rapidly growing embryonic tumor that arises in the posterior cerebellar vermis and neuroepithelial roof of the fourth ventricle.
=Pathogenesis= It is currently thought that medulloblastoma arises from cerebellar "stem cells" that have been prevented from dividing and differentiating into their normal cell types. This accounts from the varying histologic variants seen on biopsy. Rosette formation is highly characteristic of medulloblastoma and is seen in up to half of the cases.
Molecular genetics reveal a loss of genetic information on the distal part of chromosome 17, distal to the p53 gene, possibly accounting for the neoplastic transformation of the undifferentiated cerebellar cells. Medulloblastomas are also seen in Gorlin syndrome as well as Turcot syndrome. Another research has strongly implicated the JC virus, the virus that causes multifocal leukoencephalopathy.
More on [ Medulloblastoma ]
RT @CureBrainCancer: Newly discovered gene plays role in medulloblastoma tumor http://bit.ly/6yNNyp
TheKarenTrust (The Karen Trust) Sat, 12 Dec 2009 11:47:51 -0000
RT @CureBrainCancer: Newly discovered gene plays role in medulloblastoma tumor http://bit.ly/6yNNyp
Newly discovered gene plays role in medulloblastoma tumor http://bit.ly/6yNNyp
CureBrainCancer (Brain Cancer Project) Fri, 11 Dec 2009 20:35:24 -0000
Newly discovered gene plays role in medulloblastoma tumor http://bit.ly/6yNNyp
Also, congratulates to researchers at Baylor for identifying the gene linked to brain cancer medulloblastoma. http://tinyurl.com/yhyzans
UCDavisMrktg (Tom Hinds) Fri, 11 Dec 2009 01:38:00 -0000
Also, congratulates to researchers at Baylor for identifying the gene linked to brain cancer medulloblastoma. http://tinyurl.com/yhyzans
neuropsychological & bhavioral testing in young ppl w/ medulloblastoma or supr8ntorial primitive neuroectodermal tumor http://bit.ly/6ChRsA
paidtrials (US Clinical Trials) Thu, 10 Dec 2009 20:23:04 -0000
neuropsychological & bhavioral testing in young ppl w/ medulloblastoma or supr8ntorial primitive neuroectodermal tumor http://bit.ly/6ChRsA
intrathecal radioimmunothrpy, radiation thrpy, & chemothrpy after surgery in treating ppl w/ medulloblastoma http://bit.ly/8wFs8a
localtrials (US Clinical Trials ) Thu, 10 Dec 2009 12:54:55 -0000
intrathecal radioimmunothrpy, radiation thrpy, & chemothrpy after surgery in treating ppl w/ medulloblastoma http://bit.ly/8wFs8a
intrathecal radioimmunothrpy, radiation thrpy, & chemothrpy after surgery in treating ppl w/ medulloblastoma http://bit.ly/8wFs8a
usclinicaltrial (US Clinical Trials) Thu, 10 Dec 2009 12:46:51 -0000
intrathecal radioimmunothrpy, radiation thrpy, & chemothrpy after surgery in treating ppl w/ medulloblastoma http://bit.ly/8wFs8a
CancerBACUP: Medulloblastoma - Information about brain tumor that primarily affects children between the ages of three and eight. Provides general view, diagram, causes, signs, symptoms, testing, and treatment options.
Meta Description: [ Medulloblastoma is a type of brain tumour. This section describes what it is, who gets it, its causes, symptoms, diagnosis and treatment. ]
| Tumori Cerebrali Pediatrici | |
| Next Video | |
