Gourt > Health > Conditions and Diseases > Blood Disorders > Platelet
Platelets or thrombocytes are the blood cells that are involved in the cellular mechanisms of primary haemostasis that lead to the formation of blood clots. Low levels or dysfunction predisposes for bleeding, while high levels, although usually asymptomatic, may increase the risk of thrombosis.
Anatomy
Like red blood cells, platelets are anuclear (no cell nucleus) and discoid (disc shaped); they measure 1.5–3.0 μm in diameter. The body has a very limited reserve of platelets, so they can be rapidly depleted. They contain RNA, a canalicular system, and several different types of granules; lysosomes (containing acid hydrolases), dense bodies (containing ADP, ATP serotonin and calcium) and alpha granules (containing fibrinogen, factor V, vitronectin, thrombospondin and von Willebrand factor), the contents of which are released upon activation of the platelet. These granule contents play an important role in both hemostasis and in the inflammatory response.
Physiology
Production
Platelets are produced in the bone marrow; the progenitor cell for platelets is the megakaryocyte. This large, multinucleated cell sheds platelets into the circulation. Thrombopoietin (c-mpl ligand) is a hormone, mainly produced by the liver, that stimulates platelet production. It is bound to circulating platelets; if platelet levels are adequate, serum levels remain low. If the platelet count is decreased, more thrombopoeitin circulates freely and increases marrow production. More on [ Platelet ]
Liver transplant during the night. A- is lower because of that. Greatest need is for platelet donors in Sandy today and tomorrow. #utah #slc
UtahBlood (ARUP Blood Services) Wed, 04 Nov 2009 15:15:08 -0000
Liver transplant during the night. A- is lower because of that. Greatest need is for platelet donors in Sandy today and tomorrow. #utah #slc
RT @RIBloodCenter Good Morning! We need our O Neg, & A Neg WB donors and AB Neg Platelet donors to come in an donate! www.ribc.org
hotelviking (Hotel Viking) Wed, 04 Nov 2009 14:39:20 -0000
RT @RIBloodCenter Good Morning! We need our O Neg, & A Neg WB donors and AB Neg Platelet donors to come in an donate! www.ribc.org
Purvi Paliwal - dengue patient was given blessings and her platelet counts jumped She was admited to Fortis Hospital, Vasant Kunj.
aolblessings (adarsh) Wed, 04 Nov 2009 12:27:08 -0000
Purvi Paliwal - dengue patient was given blessings and her platelet counts jumped She was admited to Fortis Hospital, Vasant Kunj.
WBC, RBC, platelet CBCs..had dreams of them last night the red blood cells beat the white ones...it was odd I need2 stop studying before bed
Racerchic428 (LacySteenstraToussai) Wed, 04 Nov 2009 05:40:28 -0000
WBC, RBC, platelet CBCs..had dreams of them last night the red blood cells beat the white ones...it was odd I need2 stop studying before bed
[DCI] Give thanks for your good health-Donate Blood @ the GSA Thanksgiving Blood Drive Nov. 23rd-25th at the UCLA Blood & Platelet Center
uclaGSA (UCLA GSA) Wed, 04 Nov 2009 00:28:54 -0000
[DCI] Give thanks for your good health-Donate Blood @ the GSA Thanksgiving Blood Drive Nov. 23rd-25th at the UCLA Blood & Platelet Center
Tomorrow's MGMA Webinar: Platelet Rich Plasma (PRP) treatment and how to accurately code the procedure http://ow.ly/yYnr
mgma (MGMA) Tue, 03 Nov 2009 20:58:19 -0000
Tomorrow's MGMA Webinar: Platelet Rich Plasma (PRP) treatment and how to accurately code the procedure http://ow.ly/yYnr
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Acquired Bleeding Disorders - An article by Thomas G. DeLoughery, Associate Professor of Medicine. Platelet transfusion therapy and dysfunctional platelets are discussed.
Meta Description: [ Hemonc Home ]
Adult Chronic Immune Thrombocytopenic Purpura - A guide for patients. A description of this disease followed by an in depth look.
Idiopathic Thrombocytopenic Purpura - ITP: A look at what these words actually mean, what he causes are, who gets it, diagnosis, how it affects children and adults and pregnant women.
Meta Description: [ Information about idiopathic thrombocytopenic purpura from the American Academy of Family Physicians. ]
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Immune Thrombocytopenic Purpura - A look at the symptoms, diagnosis and treatment of this disorder. Where to look for more information.
Meta Description: [ Immune Thrombocytopenic Purpura (ITP) ]
Immune Thrombocytopenic Purpura - What it is, symptoms of ITP, diagnosis, acute and chronic forms and treatment.
Meta Description: [ Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder in which the blood does not clot as it should. ]
Platelet Disorder Support Association - Information and support for those with immune thrombocytopenic purpura and other low platelet disorders
Meta Description: [ Comprehensive information and support for those concerned about ITP, Immune (Idiopathic) Thrombocytopenia Purpura. ]
Thrombocytopenia - Features information on this disorder and its causes, incidence and risk factors.
Thrombocytopenia During Pregnancy - An in depth look at gestational thrombocytopenia, idiopathic thrombocytopenic purpura, HELLP syndrome, toxemia of pregnancy, TTP and HUS, systemic lupus erythematosus and APA syndrome.
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Virtual Hospital: Bleeding Disorders - Differentiation of platelet versus coagulation defects, presentation, bleeding caused by qualitative platelet disorders and many more topics.
Meta Description: [ Virtual Hospital was a digital library of health information in pediatrics, paediatrics, and radiology for pediatric education and radiology education ]
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