Gourt > Health > Conditions and Diseases > Blood Disorders > Blood Coagulation (1)
The coagulation of blood is a complex process during which blood forms solid clots. It is an important part of haemostasis (the cessation of blood loss from a damaged vessel) whereby a damaged blood vessel wall is covered by a fibrin clot to stop hemorrhage and aid repair of the damaged vessel. Disorders in coagulation can lead to increased hemorrhage and/or thrombosis and embolism.
Coagulation is extremely similar in all mammals, with all mammals using a combined cellular and serine protease mechanism. The system in humans is the most extensively researched and therefore the best known. This article focuses on human blood coagulation.
In brief
In a normal individual, coagulation is initiated within 20 seconds after an injury occurs to the blood vessel damaging the endothelial cells. Platelets immediately form a haemostatic plug at the site of injury. This is called primary haemostasis. Secondary haemostasis then follows—plasma components called coagulation factors respond (in a complex cascade) to form fibrin strands which strengthen the platelet plug. Contrary to popular belief, coagulation from a cut on the skin is not initiated by air or drying out, but by platelets adhering to and activated by collagen in the blood vessel endothelium. The activated platelets then release the contents of their granules, these contain a variety of substances that stimulate further platelet activation and enhance the haemostatic process. More on [ Coagulation ]
Thrombosis :: Vascular Disorders
@movieguyjon hahaha. Actually blood coagulation is serious business!! :[
patach (Patrick Cheng) Thu, 03 Dec 2009 02:33:52 -0000
@movieguyjon hahaha. Actually blood coagulation is serious business!! :[
I just published Blood Coagulation and 8 others to Scribd http://bit.ly/4ulH0K
Examville (Examville) Tue, 01 Dec 2009 21:59:57 -0000
I just published Blood Coagulation and 8 others to Scribd http://bit.ly/4ulH0K
and more » blood coagulation and skin incision applications. PRMinds (press release) ... mskincare.com
skincareffbd (skincareffbd) Tue, 01 Dec 2009 14:22:04 -0000
and more » blood coagulation and skin incision applications. PRMinds (press release) ... mskincare.com
I don't like the C word, you know 'coagulation'. thickening of the blood just irks me
Rudiology (Rudy Gardea) Sun, 29 Nov 2009 14:00:59 -0000
I don't like the C word, you know 'coagulation'. thickening of the blood just irks me
Why did I decide to make a diagram of blood coagulation? Literally the most complicated system to draw EVER!
marisol_07rx (Diane Rowland) Sun, 29 Nov 2009 09:31:58 -0000
Why did I decide to make a diagram of blood coagulation? Literally the most complicated system to draw EVER!
extremely frustrated! i'm not getting this blood coagulation crap :( i need another couple of days to... procrastinate...NOT!
jennielynnv (jenn :)) Sat, 28 Nov 2009 23:51:43 -0000
extremely frustrated! i'm not getting this blood coagulation crap :( i need another couple of days to... procrastinate...NOT!
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Guidelines on Therapeutic Products to Treat Haemophilia and Other Hereditary Coagulation Disorders - Introduction and methods, manufacture of therapeutic coagulation factor concentrates, safety data on which recommendations are based, licensing status, therapeutic guidelines, clinical audit and a review of the guidelines.
Medline Plus: Congenital Protein C or S Deficiency - Brief information about these hypercoagulability disorders including causes, treatment, and prognosis.
Medline Plus: Factor V Deficiency - Provides brief information about this inherited bleeding disorder, which is similar to hemophilia. Includes causes, symptoms, and prognosis.
Medline Plus: Factor VII Deficiency - Brief information about this inherited bleeding disorder including causes, symptoms, and prognosis.
Medline Plus: Factor X Deficiency - Information about this inherited disorder that causes abnormal bleeding including causes, treatment, and prognosis.
Medline Plus: Factor XII Deficiency - Also known as Hageman factor, this is a congenital coagulation disorder that causes prolonged coagulation in a test tube but does not cause abnormal bleeding. Includes brief information.
Molecular Genetics of Blood Clotting - David Ginsburg, M.D: An article covering von Willebrand Factor, coagulation factor V, plasminogen activator inhibitor-1, primary pulmonary hypertension and bone marrow transplantation.
Protein S Deficiency and Thrombophilia - Information about these rare medical conditions, anticoagulant therapy, research and online forum.
Meta Description: [ Information about the rare medical condition of Protein S Deficiency and Thrombophilia, anticoagulant therapy, research and online forum. ]
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The Factor VIIa Source - Information about topics related to the pathophysiology, pharmacology, and clinical aspects of bleeding, coagulation, and hemostasis, including information about recombinant coagulation Factor VIIa.
Meta Description: [ FactorVIIa.com provides information about topics related to the pathophysiology, pharmacology, and clinical aspects of bleeding, coagulation, and hemostasis, including information about recombinant coagulation Factor VIIa (NovoSeven). ]
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UIUC Hematology Resource Page - Features diagrams and information about the various thrombophilic genetic markers, general information about clotting, glossary, and list of research sources.
Viewpoint Online: Coagulation - Features articles about blood coagulation disorders including activated protein C resistance, von Willbrand's disease, and hypercoagulability.
Viewpoint Online: Coagulation - Features articles about blood coagulation disorders including activated protein C resistance, von Willbrand's disease, and hypercoagulability.
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