Cancer is a class of diseases or disorders characterized by uncontrolled division of cells and the ability of these cells to invade other tissues, either by direct growth into adjacent tissue through invasion or by implantation into distant sites by metastasis. Metastasis is defined as the stage in which cancer cells are transported through the bloodstream or lymphatic system. Cancer may affect people at all ages, but risk tends to increase with age. It is one of the leading causes of death in developed countries.

There are many types of cancer. Severity of symptoms depends on the site and character of the malignancy and whether there is metastasis. A definitive diagnosis usually requires the histologic examination of tissue by a pathologist. This tissue is obtained by biopsy or surgery. Most cancers can be treated and some cured, depending on the specific type, location, and stage. Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy. As research develops, treatments are becoming more specific for the type of cancer pathology. Drugs that target specific cancers already exist for several cancers. If untreated, cancers may eventually cause illness and death, though this is not always the case.

The unregulated growth that characterizes cancer is caused by damage to DNA, resulting in mutations to genes that encode for proteins controlling cell division. Many mutation events may be required to transform a normal cell into a malignant cell. These mutations can be caused by chemicals or physical agents called carcinogens, by close exposure to radioactive materials, or by certain viruses that can insert their DNA into the human genome. Mutations occur spontaneously, or are passed down generations as a result of germ line mutations.

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Journal of Child Health Care current issue

Children's Nursing Education: Members club or street party?
Randall, D., McTaggart, I. Wed, 20 May 2009 00:00:00 -0000

Creating space: hospital bedside displays as facilitators of communication between children and nurses
Lewis, P., Kerridge, I., Jorden, C. F.C. Wed, 20 May 2009 00:00:00 -0000
Over the past decades there has been a marked change in the physical environment of children's hospitals and the configuration of individual bed spaces. No longer the stark, clinical spaces typical of years gone by, the modern hospital bed space hosts a variety of visual displays reflecting different aspects of the child's life. Building upon ideas introduced by Lewis and informed by a recent qualitative study into hospital bedside displays, this article discusses the role that displays can play in developing, deepening and enriching relationships between nurses, patients and their families in the paediatric hospital environment. It discusses the links between hospital and home, the specific function of the display of photographs and the nurse's role in `knowing' the patient and facilitating links between hospital and home. It concludes that nurses' conscious observations of a visually rich environment may make a positive contribution to the care that they deliver for the benefit of their patients and themselves.
Influences on nurses' scoring of children's post-operative pain
Simons, J., Moseley, L. Wed, 20 May 2009 00:00:00 -0000
There is a lack of clarity as to why some nurses are not delivering optimal pain management to children post-operatively. This retrospective chart review study examined nurses' pain scoring on 175 children during the first 24 hours post-operatively. Data were analysed on the amount of assessments made, assessment scores recorded, as well as the age, gender and type of surgery performed. One-quarter of children had no assessment record of their pain in the first 24 hours post-operatively. When the pain tool was part of an observation chart, nurses recorded more pain scores. Nurses' scoring of children's pain is influenced positively by children under five years of age and those who undergo abdominal surgery. Nurses who had access to one document for recording vital signs as well as pain scores were more likely to assess and record a child's pain score than nurses who had to use a separate chart.

NPR Topics: Children's Health

Are You Over The Acetaminophen Limit?
Wed, 01 Jul 2009 15:09:00 -0400
A Food and Drug Administration advisory panel wants to reduce the public's exposure to the potent painkiller.
Congress Woozy With Health Care Sticker Shock
Sun, 21 Jun 2009 10:20:00 -0400
Guest Host Alison Stewart talks with NPR Senior Washington Editor Ron Elving about the upcoming week in Congress, and how it looks like it will be dominated by big numbers — many in red ink. The cost of overhauling the health care system is giving members of Congress sticker shock, and polls show the public is worried about the cost of multiple bailouts.
Going Gluten-Free At Age 13
Mon, 15 Jun 2009 00:01:00 -0400
Jacob Rosenblum has celiac disease, an autoimmune condition that keeps his body from processing foods with wheat gluten. Even though he can't eat his peanut butter and jelly sandwiches on wheat bread anymore, or most cereals, his family is finding new ways to cook gluten-free and keep him healthy.

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How CLIC Sargent helps children with cancer