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Diabetes insipidus (DI) is a disease characterized by excretion of large amounts of severely diluted urine, which cannot be reduced when fluid intake is reduced. It denotes inability of the kidney to concentrate urine. DI is caused by a deficiency of antidiuretic hormone, or by an insensitivity of the kidneys to that hormone.

Signs and symptoms


Excessive urination and extreme thirst (especially for cold water) are typical for DI. Symptoms of diabetes insipidus are quite similar to those of severely deranged diabetes mellitus, with the distinction that the urine is not sweet and there is no hyperglycemia (elevated blood glucose). Blurred vision is a rarity.

The extreme urination continues throughout the day and the night. In children, DI can interfere with appetite, eating, weight gain, and growth as well. They may present with fever, vomiting, or diarrhea. Adults with untreated DI may remain healthy for decades as long as enough water is drunk to offset the urinary losses. However, there is a continuous risk of dehydration.

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@ArunaMPLS ...and "insipid" can mean "bland tasting" - the urine of patients with diabetes insipidus is not sugary - it tastes bland!
PathStudent (Pathology Student) Tue, 05 Jan 2010 21:35:41 -0000
@ArunaMPLS ...and "insipid" can mean "bland tasting" - the urine of patients with diabetes insipidus is not sugary - it tastes bland!
USMLE Forums > Treatment for nephrogenic diabetes insipidus?: 3 are listed in First Aid : Thiazide, indomethacin… http://goo.gl/fb/bKsd
usmleforums (USMLE Forums) Tue, 05 Jan 2010 15:55:55 -0000
USMLE Forums > Treatment for nephrogenic diabetes insipidus?: 3 are listed in First Aid : Thiazide, indomethacin… http://goo.gl/fb/bKsd
Question: In what ways is diabetes insipidus similar to diabetes mellitus? http://bit.ly/7qPssA
medpundit (medpundit) Mon, 04 Jan 2010 13:31:59 -0000
Question: In what ways is diabetes insipidus similar to diabetes mellitus? http://bit.ly/7qPssA
A Rare Type of Diabetes- Diabetes Insipidus | Gulf Group for the ...: One of the most rare medical conditions i.. http://bit.ly/7gcwbY
ssandy81 (s.sandy) Mon, 04 Jan 2010 01:10:34 -0000
A Rare Type of Diabetes- Diabetes Insipidus | Gulf Group for the ...: One of the most rare medical conditions i.. http://bit.ly/7gcwbY
A Rare Type of Diabetes- Diabetes Insipidus | Gulf Group for the ... http://bit.ly/7ZWRSW
diabetescures (George Bright) Mon, 04 Jan 2010 01:03:00 -0000
A Rare Type of Diabetes- Diabetes Insipidus | Gulf Group for the ... http://bit.ly/7ZWRSW
A Rare Type of Diabetes- Diabetes Insipidus | Gulf Group for the ...: One of the most rare medical conditions is di... http://bit.ly/7NuWHe
joechas (joe chas) Mon, 04 Jan 2010 01:02:58 -0000
A Rare Type of Diabetes- Diabetes Insipidus | Gulf Group for the ...: One of the most rare medical conditions is di... http://bit.ly/7NuWHe

 
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