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Cushing's syndrome or hypercortisolism or hyperadrenocorticism is an endocrine disorder caused by excessive levels of the endogenous corticosteroid hormone cortisol. It may also be induced iatrogenically by treatment with exogenous corticosteroids for other medical conditions. It was discovered by American physician, surgeon and endocrinologist Harvey Cushing (1869-1939) and reported by him in 1932.
Signs and symptoms
Symptoms include rapid weight gain, particularly of the trunk and face with sparing of the limbs (central obesity), "moon face", excess sweating, telangiectasia (dilation of capillaries), atrophy of the skin (which gets thin and bruises easily) and other mucous membranes, purple or red striae on the trunk, buttocks, arms, legs or breasts, proximal muscle weakness (hips, shoulders), and hirsutism (facial male-pattern hair growth). A common sign is the growth of fat pads along the collar bone and on the back of the neck (known as a buffalo hump). The excess cortisol may also affect other endocrine systems and cause, for example, reduced libido, impotence, amenorrhoea and infertility. Patients frequently suffer various psychological disturbances, ranging from euphoria to frank psychosis. Depression and anxiety, including panic attacks, are common.
Other signs include persistent hypertension (due to the aldosterone-like effects) and insulin resistance, leading to hyperglycemia (high blood sugars) which can lead to diabetes mellitus. Untreated Cushing's syndrome can lead to heart disease and increased mortality. Cushing's syndrome due to excess ACTH may also result in hyperpigmentation of the skin, due to its ability to stimulate melanocyte receptors.
More on [ Cushing's syndrome ]
@missdibbs I have been treated for Cushing's,adrenal gland syndrome
JellieBraden (Jellie) Sun, 13 Sep 2009 22:30:07 -0000
@missdibbs I have been treated for Cushing's,adrenal gland syndrome
Cushing's Blog Post: Approach to the patient with possible Cushing's syndrome. http://ow.ly/15OMjE
cushings (MaryO) Sat, 12 Sep 2009 18:35:29 -0000
Cushing's Blog Post: Approach to the patient with possible Cushing's syndrome. http://ow.ly/15OMjE
Cushings news: : Several studies have suggested that the prevalence of Cushing's syndrome is highe.. http://bit.ly/1ahCJO
cushings (MaryO) Sat, 12 Sep 2009 18:05:47 -0000
Cushings news: : Several studies have suggested that the prevalence of Cushing's syndrome is highe.. http://bit.ly/1ahCJO
RT @cushings: Several studies have suggested the prevalence of Cushing's syndrome is higher than previously thought. http://bit.ly/2mrb0r
staticnrg (Robin) Sat, 12 Sep 2009 17:38:23 -0000
RT @cushings: Several studies have suggested the prevalence of Cushing's syndrome is higher than previously thought. http://bit.ly/2mrb0r
: Several studies have suggested that the prevalence of Cushing's syndrome is higher than previously thought. ht.. http://bit.ly/2mrb0r
cushings (MaryO) Sat, 12 Sep 2009 17:27:30 -0000
: Several studies have suggested that the prevalence of Cushing's syndrome is higher than previously thought. ht.. http://bit.ly/2mrb0r
Several studies have suggested that the prevalence of Cushing's syndrome is higher than previously thought. http://ow.ly/p6iZ
cushings (MaryO) Sat, 12 Sep 2009 17:18:53 -0000
Several studies have suggested that the prevalence of Cushing's syndrome is higher than previously thought. http://ow.ly/p6iZ
Auburn University Small Animal Teaching Hospital: Cushings Syndrome - Introduction, signs and symptoms including photographs, complications, diagnosis, therapy, and prognosis.
Meta Description: [ This is a web page designed to provide
information about the causes, signs, diagnosis, and treament of various
chronic diseases. ]
Cushings Pets Forum - Mailing list, articles, workseet for monitoring lysodren loading, personal stories, and links.
Dog Owner's Guide: Cushing's Disease - Article by Norma Bennett Woolf, which includes common drug therapies.
Mar Vista Animal Medical Center: What IS Cushing's Disease? - Introduction with animated demonstration, symptoms, tests, and pituitary and adrenal treatments.
Merck Veterinary Manual: Hyperadrenocorticism - Includes etiology, clinical signs, diagnosis, and treatment.
Meta Description: [ The Merck Veterinary Manual (MVM) has served veterinarians and other animal health professionals as a concise and reliable animal health reference for over 45 years. The Merck Veterinary Manual Online is published on a nonprofit basis through a cooperative effort of Merck & Co, Inc. and Merial L... ]
Pet Owner's Crash Course in Canine Cushing's Disease - Includes causes, diagnostic tests, the pros and cons of various treatments, and links to references.
Meta Description: [ As cushing's disease (hyperadrenocorticism) is a common disorder in older dogs, it is important for the regular pet owner to have a basic understanding of how to recognize and treat it. ]
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Vetinfo: Cushing's Disease in Dogs - Article by Michael Richards, DVM, with description, diagnosis, treatment, and answers to readers' questions.
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