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Cushing's syndrome or hypercortisolism or hyperadrenocorticism is an endocrine disorder caused by excessive levels of the endogenous corticosteroid hormone cortisol. It may also be induced iatrogenically by treatment with exogenous corticosteroids for other medical conditions. It was discovered by American physician, surgeon and endocrinologist Harvey Cushing (1869-1939) and reported by him in 1932.
Signs and symptoms
Symptoms include rapid weight gain, particularly of the trunk and face with sparing of the limbs (central obesity), "moon face", excess sweating, telangiectasia (dilation of capillaries), atrophy of the skin (which gets thin and bruises easily) and other mucous membranes, purple or red striae on the trunk, buttocks, arms, legs or breasts, proximal muscle weakness (hips, shoulders), and hirsutism (facial male-pattern hair growth). A common sign is the growth of fat pads along the collar bone and on the back of the neck (known as a buffalo hump). The excess cortisol may also affect other endocrine systems and cause, for example, reduced libido, impotence, amenorrhoea and infertility. Patients frequently suffer various psychological disturbances, ranging from euphoria to frank psychosis. Depression and anxiety, including panic attacks, are common.
Other signs include persistent hypertension (due to the aldosterone-like effects) and insulin resistance, leading to hyperglycemia (high blood sugars) which can lead to diabetes mellitus. Untreated Cushing's syndrome can lead to heart disease and increased mortality. Cushing's syndrome due to excess ACTH may also result in hyperpigmentation of the skin, due to its ability to stimulate melanocyte receptors.
More on [ Cushing's syndrome ]
#medicine #ICU #endocrine #doctors #anesthesia Cushingâs*Syndrome... http://t.co/FeZQsTsF
moheyeldin (moheyeldin aly) Sun, 22 Jan 2012 13:32:19 -0000
#medicine #ICU #endocrine #doctors #anesthesia Cushing’s*Syndrome... http://t.co/FeZQsTsF
#medicine #ICU #endocrine #doctors #anesthesia Cushingâs*Syndrome... http://t.co/Omafb7dh
moheyeldin (moheyeldin aly) Sun, 22 Jan 2012 13:31:53 -0000
#medicine #ICU #endocrine #doctors #anesthesia Cushing’s*Syndrome... http://t.co/Omafb7dh
#tourettes: Cushing's Syndrome and Dogs http://t.co/t0Jf27XS
HappyCureInfo (HappyCure) Sun, 22 Jan 2012 11:16:58 -0000
#tourettes: Cushing's Syndrome and Dogs http://t.co/t0Jf27XS
Cushing's syndrome disease in dogs http://t.co/pfSLDA0d
tiokaltspoksol1 (tiokaltspoksol1987) Sat, 21 Jan 2012 07:25:50 -0000
Cushing's syndrome disease in dogs http://t.co/pfSLDA0d
@katja_anderson I read about Capote's Swans - 'Babe' Paley. Didn't realise, daughter of Dr. Harvey Cushing.. I studied 'Cushing's syndrome'.
HarpreetKhara (Harpreet Khara) Fri, 20 Jan 2012 20:46:30 -0000
@katja_anderson I read about Capote's Swans - 'Babe' Paley. Didn't realise, daughter of Dr. Harvey Cushing.. I studied 'Cushing's syndrome'.
Cushing's Syndrome: Cushing's Syndrome provides the reader with an update onthe clinical presentation, diagnosis... http://t.co/5GIilvoZ
Hotg4meCh1ck (Ulysses Martindale) Fri, 20 Jan 2012 13:45:39 -0000
Cushing's Syndrome: Cushing's Syndrome provides the reader with an update onthe clinical presentation, diagnosis... http://t.co/5GIilvoZ
Auburn University Small Animal Teaching Hospital: Cushings Syndrome - Introduction, signs and symptoms including photographs, complications, diagnosis, therapy, and prognosis.
Meta Description: [ This is a web page designed to provide
information about the causes, signs, diagnosis, and treament of various
chronic diseases. ]
Cushings Pets Forum - Mailing list, articles, workseet for monitoring lysodren loading, personal stories, and links.
Dog Owner's Guide: Cushing's Disease - Article by Norma Bennett Woolf, which includes common drug therapies.
Mar Vista Animal Medical Center: What IS Cushing's Disease? - Introduction with animated demonstration, symptoms, tests, and pituitary and adrenal treatments.
Merck Veterinary Manual: Hyperadrenocorticism - Includes etiology, clinical signs, diagnosis, and treatment.
Meta Description: [ The Merck Veterinary Manual (MVM) has served veterinarians and other animal health professionals as a concise and reliable animal health reference for over 45 years. The Merck Veterinary Manual Online is published on a nonprofit basis through a cooperative effort of Merck & Co, Inc. and Merial L... ]
Pet Owner's Crash Course in Canine Cushing's Disease - Includes causes, diagnostic tests, the pros and cons of various treatments, and links to references.
Meta Description: [ As cushing's disease (hyperadrenocorticism) is a common disorder in older dogs, it is important for the regular pet owner to have a basic understanding of how to recognize and treat it. ]
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Vetinfo: Cushing's Disease in Dogs - Article by Michael Richards, DVM, with description, diagnosis, treatment, and answers to readers' questions.
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