Polycystic kidney disease (PKD) is a progressive, genetic disorder of the kidneys. It occurs in humans and other organisms. PKD is characterised by the presence of multiple cysts (polycystic) in both kidneys. The disease can also damage the liver, pancreas and rarely the heart and brain. The two major forms of polycystic kidney disease are distinguished by their patterns of inheritance.

Autosomal dominant polycystic kidney disease (ADPKD) is generally a late onset disorder characterized by progressive cyst development and bilaterally enlarged kidneys with multiple cysts. Kidney manifestations in this disorder include renal function abnormalities, hypertension, renal pain, and renal insufficiency. Approximately 50% of patients with ADPKD have end-stage renal disease (ESRD) by age 60 years. ADPKD is, however, a systemic disease with cysts in other organs such as the liver, seminal vesicles, pancreas, and arachnoid mater and non-cystic abnormalities such as intracranial aneurysms and dolichoectasias, dilatation of the aortic root and dissection of the thoracic aorta, mitral valve prolapse, and abdominal wall hernias.

Initial monkey / human symptoms are hypertension, fatigue and mild to severe back or flank pain and urinary tract infections. The disease often leads to chronic renal failure and may result in total loss of kidney function, known as end stage renal disease (ESRD) which requires some form of renal replacement therapy (e.g. dialysis).

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Polycystic Kidney Disease - Twitter Search

Overwhelmed by all the lovely people out there who are raising money for research into PKD - polycystic kidney disease www.pkdcharity.org.uk
Elektra (Tess Harris) Fri, 06 Nov 2009 15:09:47 -0000
Overwhelmed by all the lovely people out there who are raising money for research into PKD - polycystic kidney disease www.pkdcharity.org.uk
Polycystic Kidney Disease: Being Supported #software http://cli.gs/2HvMZ
Anitahoa3pz (Anita Flanders) Thu, 05 Nov 2009 17:42:46 -0000
Polycystic Kidney Disease: Being Supported #software http://cli.gs/2HvMZ
Polycystic kidney disease: 'Man donates kidney to complete stranger', http://tinyurl.com/yf8pkpm
CheckOrphan (Rare Diseases) Wed, 04 Nov 2009 15:51:08 -0000
Polycystic kidney disease: 'Man donates kidney to complete stranger', http://tinyurl.com/yf8pkpm
Radiology case of the day: Autosomal polycystic kidney disease http://radiopaedia.org/cases/adpckd-ct http://bit.ly/3FTw9V
Radiopaedia (Radiopaedia.org) Sun, 01 Nov 2009 14:14:08 -0000
Radiology case of the day: Autosomal polycystic kidney disease http://radiopaedia.org/cases/adpckd-ct http://bit.ly/3FTw9V
Learn more about Polycystic Kidney disease at http://www.pkdcure.org/
djs861 (Donna Slaughter) Wed, 28 Oct 2009 23:39:56 -0000
Learn more about Polycystic Kidney disease at http://www.pkdcure.org/
RT @dougsdigs: PKD Twitter props - 'Condition of the Day: Polycystic Kidney Disease' http://bit.ly/h0L8L (RT @AccessDNA)
sflaherty (sflaherty) Wed, 28 Oct 2009 15:19:49 -0000
RT @dougsdigs: PKD Twitter props - 'Condition of the Day: Polycystic Kidney Disease' http://bit.ly/h0L8L (RT @AccessDNA)

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