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Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed as its hydrochloride salt, naltrexone hydrochloride, under the trade name Revia. In some countries, an extended-release formulation is marketed under the trade name Vivitrol.
Chemical Structure
Naltrexone can be described as a substituted oxymorphone – here the tertiary amine methyl-substituent is replaced with methylcyclopropane.
Pharmacology
Naltrexone, and its active metabolite 6-β-naltrexol, are competitive antagonists at μ- and κ-opioid receptors, and to a lesser extent at δ-opioid receptors. This blockade of opioid receptors is the basis behind its action in the management of opioid dependence—it reversibly blocks or attenuates the effects of opioids. More on [ Naltrexone ]
Assisted Recovery Center of Georgia - Treats alcohol and opiate addiction using a combination of behavioral modification therapy along with naltrexone.
Meta Description: [ Drug and alcohol treatment at the Assisted Recovery Center of Georgia helps people with drug addiction & alcohol abuse problems in a non-12 step program environment utilizing the medication of Revia (naltrexone). ]
Naltrexone - The Alcoholism Drug Fails Sobriety Test - An article by Adam Marcus on the extent to which this pill can aid in cutting down alcohol intake.
Meta Description: [ A new study which questions how far medication is useful in treating alcoholism ]
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