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Phencyclidine (a contraction of the chemical name phenylcyclohexylpiperidine), abbreviated PCP, is a dissociative drug formerly used as an anaesthetic agent, exhibiting hallucinogenic and neurotoxic effects.

PCP was commercially developed in the 1950s by the Parke-Davis pharmaceutical company. Internationally, PCP is a Schedule II drug under the Convention on Psychotropic Substances."List of pychotropic substances under control, in accordance with the Convention on Pychotropic Substances of 1971": Report from 2003 (pdf)

Chemistry and pharmacology


Chemically and pharmacologically it is a member of the family of dissociative anesthetics, which also includes ketamine, tiletamine and high doses of dextromethorphan. Although the primary psychoactive effects of the drug only last hours, total elimination from the body is prolonged, typically extending over weeks.

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Meta Description: [ Rewarding actions of phencyclidine and related drugs in nucleus accumbens shell and frontal cortex. ]

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